Good Lifestyle

COVID-19 vaccinations saved 2.5 million lives Between 2020 and 2024, according to a new study of comparative efficiency. Similar to the flu, health experts say the best defense against Covid Stay up to date with the most recent vaccine. But some variants strike stronger than others, especially in children, the elderly and immunocompromised people. Although it is not unusual for the symptoms covored to linger for several days or even weeks after a negative test result, the symptoms that persist three months or more after the start are an indicator of the long cocvid.

Chronic state May feel "similar to autoimmune, pulmonary, cardiac, neurological or psychological disorders. Some symptoms are light and others are completely debilitating. They can come and go, change or worsen over time.

It is estimated that five to 10% of cases lead to a long coide. In addition, most patients do not feel "back to normal" for 12 to 18 months.

Despite the evolution of the COVVI-19 vaccine, there is no approved test for the diagnosis long .

"If a patient arrives in the clinic and tells the persistence of signs and symptoms typical of long infection, 12 weeks or more after an infection at -19, I give them an alleged diagnosis, but I have no blood tests or biomarkers to confirm this diagnosis," William Stnger , MD, an investigator of the Lundquist Institute, said in A press release .

However, Stringer and a team of scientists believe that they are about to identify a potential potential potential biomarker. If it is corroborated by other research centers, the biomarker would be the first "quantifiable indicator" of the genus.

In relation: A new cocovated strain is propagated, which warns - the symptom n ° 1 namely .

The study, which appears in the review Infection , was led by researchers from the Translational Genomic Research Institute of the City of the City of the City (TGEN) and the Lundquist Institute for Biomedical Innovation at the Harbor-Ucla Medical Center.

More specifically, they sought traces of fragments of SARS-COV-2 protein in extracellular vesicles (EV). These proteins do not naturally exist in healthy human cells, leading scientists to hypothesize that their presence could be a clear biomarker for the long coide.

"Emerging evidence suggests that the SARS-COV-2 viral RNA and viral antigens can persist in various tissues (lung, brain, muscles, lymph and plasma nodes) for months after acute infection, and can be pathogenic for common current symptoms", wrote the authors.

They also explained: "Nanose vesicles which facilitate intracellular communication of bioactive molecules such as proteins, lipids, nucleic acids and metabolites - have proven to host other RNAs and viral proteins, and can potting viral replication, immune activation and inflammation."

For the study, the researchers have analyzed 56 blood samples of 14 people who have had a covid in the last two years and / or people with long symptoms covers, such as fatigue, shortness of breath and lack of energy.

Their analysis detected 65 fragments of distinct SARS-COV-2 proteins within EVs.

"The analysis of the sequences confirmed that these peptides were specific to SARS-COV-2 and did not overlap with human proteins. Since then, each subject presented one or more peptides SAR-COV-2 in their EV cargo, suggesting the persistence of viral components over time," wrote the authors.

These results fuel an increasing abundance of research that suggests that the covored variants can linger and surrender in tissues, plasma and muscles long after the first manifestation of symptoms. A biomarker of this stature could speed up diagnostics and help patients get treatment quickly.

In relation: Scientists find a shocking link between Covid and Alzheimer .

But although promising, the authors said that there was "still a lot to unpack".

"We have not carried out [our tests] on people without very long symptoms who are currently, or who were, infected with the coide," said Strnger. "This raises the question: does this continue to remove the trash can from the infected cell in the trash or is it really in progress somewhere? I think that is the mechanistic question that must be resolved in future studies."