Good Lifestyle

Growing research indicates that metformin could help prevent And treat colorectal cancer, which is quickly increasing from young generations. As Best life Previously, "metformin is a hypochometric drug by blood sugar used to treat type 2 diabetes". And now researchers say that the tablet could also have positive effects on the drop in dementia and the risks of Alzheimer in obese adults.

In relation: Doctors warn that common drugs can be linked to the risk of dementia .

Some people could reduce their risk of dementia with the treatment of metformin.

The metformin of common diabetes drug can protect against dementia and Alzheimer's disease in overweight and obese adults, according to new research published in the journal Diabetes, obesity and metabolism . The drug was also linked to "significantly lower" risks "of mortality.

To achieve these results, scientists attributed 452,777 individuals to a group according to their body mass index (BMI). These represented an overweight BMI and the four different levels of obesity.

According to the centers for Disease Control and Prevention (CDC), these levels are defined as:

• Surposndole: BMI beach from 25 to 29.9
• Class I obesity: BMI beach from 30 to 34.9
• Class II obesity: BMI beach from 35 to 39.9
• Severe obesity: BMI beach 40 years and over

Participants were prescribed from metformin, although each BMI group also had certain people who did not use metformin and served as a control group.

During a 10-year follow-up period, the researchers recorded the number of dementia and deaths all causes of causes between users of metformin and non-factories in the four groups. There were 35,784 dementia diagnostics and 76,048 deaths in all combined cohorts.

However, "users of metformin presented considerably lower risks of dementia and death all causes than non-users", described the authors A press release .

In addition, the advantages of metformin were obvious in all BMI groups, not only those classified as "severe obesity". The researchers observed a 8 to 12 percent reduces the risk of dementia and a 26 to 28% have reduced the risk of mortality in users of metformin.

In the future, the authors said that additional research was necessary to collect a more complete understanding of the effects of metformin.

"Although the results of our study are promising for the effects of metformin on dementia and mortality, additional research is necessary to explore the mechanisms involved", co-author Chiehfeng Chen , Said PhD, in the press release.

In relation: Scientists say that this “cheap” treatment could reverse Alzheimer's disease .

Previous studies support the use of metformin to reduce the risk of dementia.

Previous research has presented the health benefits of using metformin to reduce the incidence of dementia.

An article from 2023 published in Jama Network Open concluded that stopping Metformin treatment is linked to an increased risk of dementia. The study focused on diabetic patients who already used metformin to help manage insulin levels.

"The termination of the treatment of metformin was associated with an increased incidence of dementia, corroborating previous observational research according to which the initiation of metformin was associated with a reduced risk of dementia," wrote the authors. "This observation has important implications for clinical management of diabetes."

Doctoral students from the University College London also undertook to explore the effects of Metformin on Alzheimer's disease. In a proposal Explaining their thesis for the study, they called for previous research which ruled against the neurological advantages of metformin. They decided to understand the "bad" and "good" effects of the drug.

"It has also been shown that the treatment of metformin increases the accumulation of amyloid proteins (a characteristic of Alzheimer's disease) in the brain, which is an undesirable negative effect. Consequently, there is a real need to understand in more detail how Metformin Interagit with the brain of Alzheimer's disease", reads the document.

A 2018 study suggests That diabetic patients could gain metformin to reduce the risk of dementia and Alzheimer's.