Ozempic modifies the personalities of certain patients and doctors think to know why
Some patients said they had no more interest in certain vices.
When you read on Ozempic, you have to hear about the Potential side effects . The drug, which is indicated for the treatment of type 2 diabetes, is often prescribed out of AMM for weight loss - and although it is certainly effective, some patients have reported gastrointestinal problems (GI) and a series unpleasant complications. But although these side effects can be debilitating for some, there have also been reports of agonist from Peptide -1 of the Glucagon type (GLP -1) - The Ozempic Medication Class and its sister medicine, Wegovy, fall - scaring patient personalities.
In relation: Ozempic patients reveal a major side effect when you stop taking it .
Some patients have pointed out that ozempic reduced their libido , while others have noted that it had really slowed down their interest Vices like alcohol . It may seem a little mysterious of the reason why it happens, but doctors say that there could actually be a clear reason for these changes.
As experts explained in the conversation with the Daily mail , dopamine is a key factor here. According to the Cleveland Clinic, dopamine is " reward center "In your brain, offering you a feeling of pleasure and motivation to do something when you feel these effects. Food and substances activate these signals in our brain.
Ozempic works by imitating the GLP-1 hormone in your body, slowing down gastric emptying and making you feel more. According to Kent Berridge , PHD, professor of psychology and neuroscience at the University of Michigan, this affects your food desires, but it can also affect other desires.
"Satiety can not only reduce the thirst for food, but potentially for other things," Berridge told Daily mail .
In fact, when people are hungry, the desires of things like addictive drugs are also amplified.
"When researchers try to bring animals to learn to self-administer cocaine, they will often keep them hungry for a while, because it helps them to learn," said Berridge. "Hunger is specifically for food, but it is more general than that, it activates the thirst for many things. If you are hungry, the motivation value of things, even which are not food, seems to increase . "
In relation: An ex-ozempic patient shares the side effect which will not disappear .
It may also be that desires are moderate, because patients in Ozempic still eat, but not as much as they did before they are under medication.
"It would be a possibility - to do [the edge of certain desires], and it is those that are problematic if you try to lose weight or if a person tries to stop taking drugs," added Berridge.
In terms of decrease in libido or interest in having sex, Berridge also offered an explanation for this. When the reward for this is removed, patients may not be as interested in physical intimacy.
"If you delete a little [activation of dopamine] and you reduce these mountain peaks, sexual desire is a natural peak, so it would be plausible," said Berridge to the Daily mail .
However, the question remains as to the way Ozempic removes dopamine, according to Berridge.
"It can act in part on the core accumbens [the structure of the brain known for its role in pleasure, reward and dependence], because there are receivers there," he told the newspaper.
There are other theories that dopamine can become so deleted because of these drugs that this could lead to conditions such as anxiety and depression. Although it is not "impossible", according to Berridge, people may have been depressed in advance, or they could suffer from a condition called Anhedonia, where they lose the ability to want pleasure.
"'Pleasure [gets] normal notes but nothing has value in life, and that's a problem," he said Daily mail On Anhedonia. "If [ozempic] caused problems of this kind, I expected it to do so - an evolution rather than a real loss of pleasure."
In relation: Ozempic patients go to the emergency room on "serious" side effects .
In addition to that, another expert speaking with the Daily mail shared that Ozempic could change the personalities by reduce depression.
"I think it regulates dopamine: it can raise it and it can reduce it, but basically, it keeps it in a stable range", " prosecute Decay , MD, a weight loss doctor based in New York, told The Outlet. "I have seen a lot of depression inversion in patients, because when you improve the action of dopamine, you really reduce depression, anxiety, compulsive behaviors such as play and alcohol consumption , and all these things, even people are not part 'I feel the need they have to go out and do that more.
It should be noted that the Food and Drug Administration of the United States (FDA) hundreds or reports Psychiatric disorders linked to three of the treatments of Novo Nordisk - Ozempique, Wegovy and Saxenda - In 2023, The New York Post reported. The regulation agency requires that drugs like Saxenda and Wegovy have warnings on suicidal thoughts because they are indicated for weight management and work on the central nervous system, but Ozempic is not required to have it because it is only approved for diabetes.
The FDA confirmed that its reviews of clinical trials Not found connections Between these drugs and the occurrence of suicidal thoughts or actions. However, the agency could not "definitively exclude that a low risk may exist". After a nine-month exam, the European Medicines Agency also concluded that "the available evidence does not support causal associations" between GLP-1 and Suicidal thoughts or actions .
Better life Contacted Novo Nordisk to comment on the reports of personality changes, and we will update history with the business's response. AE0FCC31AE342FD3A1346EBB1F342FCB
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