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To blow out of the 100th anniversary candles is a success of life, a majority of us that can only dream. Attacking the supercintenary status is also a high step. But become a super-aging? Now it may be the most elite Click among the living. Super-agents are Known to have an impeccable memory , better mental health and more active lifestyles than their young peers. Do you want to join this secret club? Researchers have just identified four things that all super-agents have in common.

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What is a “super-agency?

Northwest medicine scientists define " super-agents "As adults over 80 years old," who have the memory capacity of people who have at least three decades less. ""

Super-agents are "very social" and have brains that "resist the accumulation of plates and tangles linked to Alzheimer's".

Director brain research From their own tuft scientists explained: "The pathology of Alzheimer's disease described the abnormal accumulation of two proteins in the brain - amyloid and tau - which group together, forming plates and tangles which are supposed to disrupt the function of brain cells."

Based on a 2025 report of the Alzheimer's association, a estimated 7.2 million Americans live with Alzheimer's disease. We think that one in nine people aged 65 and over has the disease, although we know that the prevalence increases with age. The association reports that 5.1% of people aged 65 to 74 develop Alzheimer's ; This statistic increases almost seven among people aged 85 and over.

However, super-agents seem to be safe from these rattling statistics.

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Super-agents have four joint features.

Over the past 25 years, experts from the Mesulam Center for Cognitive Neurology and Alzheimer's disease have studied nearly 300 suckers and 77 autopsied on superage brains.

Sandra Weintraub , PHD, professor of psychiatry and behavioral and neurology sciences at the Northwestern University Feinberg School of Medicine, called insights from the Brain Autopsies "Bringing" for experts in his field.

Although some super-agen brains have shown protein tufts linked to Alzheimer's, others did not have the presence of dementia / Alzheimer's indicators.

"What we have achieved is that there are two mechanisms that lead someone to become a super-age," said Weintraub. "One is a resistance: they do not make plates and tangles. Two is resilience: they do them, but they do nothing to their brain."

But what they discovered is that super-agents share these four features:

• Exceptional memory performance : The results of the recall tests for delayed words were tied with 50 to 60 years.
• Young brain structure : There was "no significant slimming" of the outer layer of their brain. "This crucial region of the brain plays an important role in the integration of information related to decision -making, emotion and motivation," said the researchers.
• Unique cellular lines : The increased quantity of von Economic neurons (associated with social behavior) and more important entorhinal neurons (linked to memory), compared to aging "typical" peers.
• Sociability as a common trait : The Superages are "very social" and maintain "solid interpersonal relationships".

The results should be published in Alzheimer's and dementia: the newspaper of the Alzheimer's association .

However, scientists have not yet identified how A person becomes a super-age. Does this have to do with eating or lifestyle? Can it be reduced to genetics? Do certain drugs or environmental factors reduce your risk of becoming a super-age? These are all questions that experts hope to answer "by identifying the biological and behavioral features" linked to supervision.

Researchers also hope to determine new strategies that stimulate cognitive resilience, as well as delay or prevent dementia and other diseases of cognitive disorders.

"Our results show that an exceptional memory in old age is not only possible, but is linked to a distinct neurobiological profile. This opens the door to new interventions aimed at preserving brain health until the last decades of life," concluded Weintraub.