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After obtaining Hollywood recognition in 2021, GLP-1 drugs are still as popular. Ozempic , the queen bee of these weight loss drugs is only approved to treat type 2. diabetes. However, this did not prevent celebrities and the average patient from using the medicine out of AMM as an appetite suppressor. But with these advantages that hinder the figures come a score of potentially dangerous side effects, one of which has very concerned doctors.

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Doctors are concerned about muscle loss linked to ozempic.

Without the appropriate dietary guidelines in place, taking GLP-1 drugs can be a slippery slope, have warned many doctors.

"It is this constant fight between eating protein and ensuring that you meet your nutritional needs, then to take this medication that does not allow you to eat," said the anesthesiologist Nicole Martin , MD, on her Scrubs to stilettos podcast.

This merry -go -round can ensure that patients become "nutritional deficient" and " fatty », A term used to describe someone with a low BMI (body mass index) but the lack of muscle density.

"When you limit your calories, and you do not eat well and you do not exercise, now you lose lean muscle mass," said Tiffany Moon , MD, doctor and Scrubs to stilettos Co-host of the podcast.

As Best life Previously reported, "strong muscles contribute to the prevention of osteoporosis, the protection of articles, bone growth and better balance. A study in 2024 published in Jama Network Open found that taking GLP-1 medication led to Decrease in muscle mass and increase in bone mineral density (DMO). »»

This alarming side effect was also reported in a recent study by nutrition experts from the University of Utah College of Health.

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GLP-1 drugs can lead to a 10% reduction in lean muscle mass.

GLP-1 and Ozempic drugs can reduce lean muscle mass by around 10%, according to a new study published in the journal Cellular metabolism .

A drop in lean body mass - defined as "a body weight that is not fatty" - can disturb your energy levels, your skeletal muscles and your bone force, "potentially compromising physical functions and quality of life, especially in people sensitive to sarcopenia", warned the authors.

In a preclinical mouse model, researchers observed negative changes in lean mass and muscle effort. In particular, around 45% of weight loss was attributed to a reduction in lean mass. The skeletal muscle also decreased by six percent, and "they found that, for certain muscles, the force decreased as the mice lost weight", according to the press release .

The authors warned against "drawing a parallel one by one with humans", noting that weight gain and loss have variable effects on mice and humans.

However, these results corroborate previous theories on the undesirable effect of Ozempic on lean muscle mass. In fact, their research is linked to an AARP 2023 report which revealed "for each book you lose, About 25% is muscle and bone. »»

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Ozempique is also known to cause bone loss.

Bone fragility and weaker muscles are a natural sign of aging; However, certain drugs, such as Ozempic, can accelerate these changes in adults 65 years and over.

"Significant weight loss, especially on a short period of time, can also contribute to a decrease in bone density, which can put older adults to an increased risk of bone fractures or exacerbate pre -existing conditions such as osteoporosis", " HAVY NGO-HAMILTON , Pharmd, pharmacist and clinical consultant at Buzzrx , previously explained to Best life .

In addition, this can make this age group more sensitive to "health, disability and mobility problems," she added. Therefore, many health officials do not encourage ozempic treatment in geriatrics.