The comfortable type vaccine could help heal "each patient with cancer", announces scientists

MRNA technology has proven to help fight tumors in a recent mouse experience.


No matter how young you are, healthy or proactive, scary truth is that anyone can be diagnosed with cancer. According to the National Cancer Institute (NCI), More than 2 million patients In the United States, will probably be diagnosed with a certain form of the disease this year - and more than 618,000 people will die.

However, there are also around 18.1 million cancer survivors in the United States, thanks in part to the fact that research and technology continue to improve our ability to detect the disease early and treat it effectively. But what happens if the long-standing objective to heal or completely prevent cancer was somehow a reality? Scientists now say that a new Covid type mRNA vaccine could help heal "every cancer patient" based on new research.

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New research suggests that mRNA vaccines could fight against tumors.

In a study published in the journal Biomedical engineering of nature On July 18, a team of researchers from the University of Florida (UF) shared A revolutionary discovery Made in a laboratory experience conducted on mice.

By combining an mRNA style vaccine with traditional cancer immunotherapy drugs called immune control point inhibitors, they have generated a response to rodent tumors, suggesting that technology could be used to stimulate the body's immune system to protect against cancer .

"This article describes a very unexpected and exciting observation: that even a vaccine not specific to a particular tumor or virus - as long as it is a mRNA vaccine - could lead to specific effects for tumor", " Elias Sayour , MD, PHD, the lead in study and a pediatric UF health ones, said in a press release. "This observation is proof of concept that these vaccines could potentially be marketed as vaccines against universal cancer to raise awareness of the immune system against the individual tumor of a patient."

How do mRNA vaccines work?

If the term " mRNA vaccine "Gives you flashbacks to the pandemic, it should not surprise. The technology has been used in the production of COVID-19 vaccines by Pfizer-Bion-Biontech and Moderna, and is currently one of the only generalized uses of treatment, according to the Cleveland Clinic.

Like other vaccines, mRNA versions work by starting the body to combat invaders and potential pathogens that can be harmful. However, this new technology does not depend on the use of dead or weakened versions of a virus (or parts of a virus) to generate an immune system response and provide antibodies.

These vaccines use mRNA (or molecule which transports the plans for protein production in our cells) which provides the information necessary for the body to produce specific proteins.

So how does it work in practice? In the case of COVID-19, this means that the shots bear the mRNA necessary for cells to produce the unique cutting-edge protein of the virus. The cells then produce this single piece, which the body then considers as an invader and begins an immune response to eliminate it, creating a roadmap that helps protect against future infections by the real virus.

The mRNA injected into the body within the framework of the vaccine is broken down a few days following the reception of the shooting (just like the mRNA of the human body within the framework of cellular metabolism).

The development of safe and effective COVI-19 vaccines based on mRNA that has saved countless lives has been developed and administered rapidly, but the technology on which they are based have been the subject of intense research since the 1970s, according to the Cleveland Clinic.

After finally developing a way to administer mRNA without the body destroying it in recent decades, technology has been approved for the first time seven years ago for a drug used to treat a rare nervous disorder before its use during the pandemic.

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The latest study is based on other promising research.

Last year, Sayour successfully used mRNA technology to treat glioblastoma (an aggressive form of brain tumor) in a human test. In this case, the patients received photos of mRNA according to the specific tumor cells drawn from their bodies which allowed the immune system to set up a more "vigorous" response, according to a press release.

For the latest study, scientists used mRNA technology to treat different forms of cancer in mice. However, instead of drawing specific cells and manufacturing vaccines specific to each tumor, scientists have been successful when experimenting with a general version administered alongside a typical form of monoclonal antibodies used in the treatment of cancer.

For the next phase of experience, researchers have treated mice with brain, skin and bone cancers using only the mRNA vaccine. Even without the use of additional treatments, the team noted "beneficial effects", certain tumors being even completely eradicated by technology.

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What does this mean for the future of cancer treatment?

The team concluded that mRNA vaccines could be an effective tool to mitigate the body to use its resources to fight different forms of cancer.

"This study suggests a third emerging paradigm", " Duane Mitchell , MD, PHD, one of the study co-authors, said in a press release. "What we have found is by using a vaccine designed so as not to target cancer specifically but rather to stimulate a strong immunological response, we could cause a very strong anticancer reaction.

Mitchell added that although there is a good chance that mRNA technology could be used in conjunction with other treatments, there is a good chance that the vaccine itself can be effective in the future. The team said that she was now working to continue her research by launching a human clinical trial after finalizing new formalizations.

"This could potentially be a viable approach for each patient with cancer," said Sayour in an interview with the Tampa Bay Times .

In relation: 14 types of cancer increase in Americans by less than 50 .

The point to take away:

The same technology that helped save countless lives during the COVVI-19 pandemic can now be able to do the same against another formidable enemy: cancer.

Researchers from the University of Florida have found that mRNA vaccines have caused a robust immune response in mice with different forms of illness. Remarkably, the team saw positive results when using a more generalized version of the vaccine than what had been used in previous studies - in some cases by completely removing tumors.

"This could potentially be a universal way of waking up a patient's immune response," Mitchell said in a press release. "And that would be deep if it was generalizable to human studies."

We offer the most up -to -date information for high -level experts, new research and health agencies, but our content is not supposed to replace professional advice. Regarding the medication you take or any other health issue you have, always consult your health care provider directly.


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