4 supplements that can stimulate your mood, proven by science

Spoiler alert: Magnesium and Ashwagandha are not on the list.


Plant remedies are not an appropriate substitute for speech therapy and prescription drugs, but experts affirm that they are one of the most commonly used self -edited methods. According to a set of data Centers for Disease Control and Prevention (CDC), 21 million adults and 3.7 million adolescents in the United States said they had at least one major depressive episode in 2021.

It is expected that 61% of adults and 40.6% of adolescents received treatment, respectively. However, in Great Britain, it is estimated that less than 15% of people with depressive symptoms receive treatment.

A new study published in the journal Borders in pharmacology qualifies certain plants based on plants such as "a popular part of preventive care and support for depressive symptoms". However, there are more that are not deemed credible by scientists.

In relation: This unusual supplement can improve your sleep and your mood, says a new study .

New research examines how plant -based supplements and vitamins can affect depression.

Compared to prescribed therapy and drugs, supplements based on over -the -counter plants and vitamins are relatively profitable and more widely accessible, making it a more attractive alternative for those who may not have insurance or who are nervous about potential side effects.

"It is suggested that natural products, such as plants based on plants or nutrients, can help manage depression through various mechanisms, including inhibition of inflammation, improvement of oxidative stress, modification of the axis of microbiota-but-Brain, the suppression of hyperactivity in hypothalamic-pituaries and the reduction of neurotrans issuers, ”wrote the authors of the study.

Many people consider low -risk supplements. However, experts warn that a majority of supplements promoted for depression have not been deepened and studied for this specific line of use. In other words, when you zoom in, there is no scientific evidence that they really help with depressive symptoms.

In addition, supplements come with their own crowd of possible side effects. You should also be aware of how supplements can interact with other drugs you already take.

"It is in a way the Far Wild West with the understanding of the supplements", " Thea Gallagher , Psyd, clinical psychologist at the Nyu Grossman School of Medicine and director of wellness programs at Nyu Langonehealth, said Health . (Gallagher was not involved in the study.)

"There are a lot of influencers who are paid to say that something has worked for them, but the problem when you come from science and research, we do not see that scientific results are robust enough for us to recommend," she said.

In relation: 12 supplements that you should never take together, say medical experts .

Out of 64 supplements, only 4 are considered safe and effective for depression.

To prove their point, the researchers examined 64 different types of supplements in 1,367 studies and 209 clinical trials.

Surprisingly, 41 supplements were only tested in a single test. The remaining products were organized in lists classified according to their efficiency. Here is what they discovered.

Supplements with mixed evidence:

  • Melatonin
  • Magnesium
  • Curcumin
  • Cinnamon
  • Failed
  • Vitamin C
  • Vitamin D
  • Calcium

Supplements deemed "promising" for the treatment of depression, but require additional research:

  • Folic acid
  • Lavender
  • Zinc
  • Tryptophan
  • Rhodiola
  • Lemon balm

"Among these, chamomile, lavender, lemon meton and echium represent products commonly used and should have priority for new research on their safety and efficiency," according to the authors.

At the end, Only four supplements were determined to be " relatively established products. " They are:

  • Omega-3
  • St. John’s Wall
  • Saffron
  • Probiotics

Data has shown that saffron is "not significantly different from antidepressants" and omega-3s have "significant effects to reduce depressive symptoms compared to placebo".

In fact, a study in 2021 published in the journal Molecular psychiatry found that Omega-3 supplements Can considerably reduce the amount of cortisol, a stress hormone, in the body.

The must of Saint-Jean "showed similar efficiency and lower abandonment rates compared to antidepressants" in 27 studies .

Interestingly, probiotics have reduced depressive symptoms against placebo, "with greater effects observed in people with major depressive disorders".

At this point, a recent study published in the journal NPJ mental health research noted that by increasing the "good" bacteria in the intestine, probiotics can reduce negative mood in just two weeks.

Health managers call for the revealing study and urging people to reconsider the products with which they store their pharmacy cupboards.

“This study is a really useful snapshot of where we stand with depression supplements. What marked me the most was that they examined 64 different products but found solid evidence for only four "," By Borrah Wright , MD, medical director of hospital psychiatric services for children and adolescents at NYC Health + Hospitals - Kings County, said Health .

As with starting any new medication, including supplements, it is important to do your research. No complement is created equal, and it is not because it works for someone other than it will work for you.

Talk to your doctor if you feel feelings of depression and / or plan to add a new product to your health regime.

We offer the most up -to -date information for high -level experts, new research and health agencies, but our content is not supposed to replace professional advice. Regarding the medication you take or any other health issue you have, always consult your health care provider directly.


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