Doctors discover optimal time to take your drug against hypertension

Only 20% of those who take these drugs have their hypertension under control.


It is estimated that almost half of all American adults have hypertension, or high blood pressure , which is a risk factor for heart disease and stroke. However, according to the Centers for Disease Control and Prevention (CDC), only about 59% are aware Let them suffer from hypertension - almost the same number which currently takes medication to lower their blood pressure.

But from the group taking medication, only 20% have under arterial control. There are many possible reasons for this, including lifestyle factors such as diet and exercise, as well as not to see the doctor regularly to assess current drug doses. And according to a new study, the day of the day that you take your medicine from blood pressure can also considerably affect its operation.

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The researchers compared the dosage of the drug against blood pressure in the morning and bedtime.

For a new study published this week in the journal Jama Network Open , the researchers carried out a clinical trial to find out if taking hypertension medication in the morning or at bedtime proved to be more effective.

To achieve their results, they enlisted 720 patients with hypertension, who all had no antihypertensive treatment or interrupted these drugs for two weeks before the study.

The participants were divided into two groups, one who took hypertension medication in the morning, between 6:00 am and 10:00 am, and another who took medication at bedtime, between 6:00 p.m. and 10:00 p.m.

Whatever the dose time, the participants all received 20 mg of Olmesartan , a receiver blocker of angiotensin II (ARB), as well as 5 mg of amlodipine , a blocking channel blocker. The study lasted 12 weeks, but the quantities of dose were adjusted in weeks 4 and 8 depending on the blood pressure measures of each individual.

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Taking drugs against blood pressure at night proved to be more effective.

The researchers determined that "the bedroom dosage has provided better control of the night blood pressure and improved the circadian pace, without reducing efficiency on the ten average or the 24 -hour blood pressure, nor increase the risk of night hypotension."

In other words, the two groups had similar blood pressure readings during the day, but the bedtime group had healthier blood pressure readings during sleep (nocturnal blood pressure).

As MedicalNewSTODAY Explains: "As a rule, blood pressure decreases from 10 to 20% during the night, because it follows the natural circadian pace."

When this does not happen, it can cause a frequent awakening to urinate, sleep apnea and difficulty breathing. It can also the risk of Heart disease, cerebral vascular accidents, diabetes, metabolic syndrome, obesity and renal failure.

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What does this research mean for you?

Most importantly, never change your medication diet or your schedule without consulting your doctor first.

There were also several limits under study, especially that all participants came from China and had no cardiovascular disease. In addition, it was a short -term study and only represented specific drugs.

However, the researchers wrote that they thought that the results "support the potential advantages of bedtime administration" and offer new evidence to seek research on antihypertense chronotherapy, which uses a person's circadian rhythms to timed their doses of drugs.

We offer the most up -to -date information for high -level experts, new research and health agencies, but our content is not supposed to replace professional advice. Regarding the medication you take or any other health issue you have, always consult your health care provider directly.


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By: liudmyla
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