The ozempic future alternative could "minimize side effects", say the researchers

It is a capsule rather than an injection, and it always produces impressive weight loss results.


Ozempic , which is manufactured by Novo Nordisk and indicated for the treatment of type 2 diabetes - as well as its sister medication, Wegovy, indicated for weight loss - helped patients lower the spectacular weights of weight. But despite their impressive results, these drugs are not without risk, because they are sometimes known to cause Painful side effects . The most commonly known symptoms associated with the injection of semaglutide (the active ingredient in ozempic injection and wegovy) are gastrointestinal, some patients with sufficiently serious symptoms for interrupt treatment . However, an ozempic alternative is in development, and the researchers say that it could "minimize the side effects" associated with other weight loss treatments.

In relation: The ozempic patient reveals a new "repulsive" side effect .

Massachusetts Institute of Technology (MIT) engineers have developed a unmanageable capsule It plays on a "phenomenon" that your body uses to tell you that you are full after eating a big meal, by press release.

Your stomach naturally sends signals to your brain to let him know that you can stop eating, but the new pill - well known as an unmanageable bioelectronic stimulator (vibrations) - recites this sensation by vibrating in your stomach and activating The same receptors expandable in the sense resembling this sense when your belly is distended. In doing so, you get a "feeling of illusory fullness", said the press release. AE0FCC31AE342FD3A1346EBB1F342FCB

"For someone who wants to lose weight or control their appetite, it could be taken before each meal", " Shriya Srinivasan , PHD, former student graduate of MIT and Postdoc, and current assistant professor of bio-engineering at Harvard University, in the press release.

According to the press release, when pork is given 20 minutes before eating, the pill favored the release of hormones which signal fullness and also reduced the food intake of animals by 40%. According to official study Published in Scientists progress On December 22, animals also had a minimized weight gain rate compared to animals that did not take the vibration pill.

The pill must be "activated" in the stomach to start vibrating, which it does for about 3o minutes after reaching the stomach. In the new study, the pill crossed the digestive pathways of animals in four to five days - and during this time, the researchers noted that animals showed no sign "obstruction, perforation or other negative impacts" . Researchers also noted that when observed in more than 20 trials in a large animal model, vibrations have produced no "observable distress or negative side effects".

"[Vibrations] could be really interesting in that it would provide an option that could minimize the side effects we see with other pharmacological treatments," Srinivasan said in the press release.

In relation: Ozempic patients say that "stops working" for weight loss - how to prevent this .

Researchers think that vibrations could offer a viable option to those who have had trouble with the side effects linked to Semaglutide injection Or shooting (known as Eli Lilly's brand names Mounjaro And Zepbound ). Some have reported painful stomach conditions such as gastropares, as well as problems with gallbladder, which also landed patients in the emergency room .

However, in addition to reducing side effects, the new capsule could increase access to weight loss drugs by offering a more affordable option, researchers said. GLP-1 agonists, such as semaglutide, can be particularly expensive, they added.

"For many populations, some of the most effective therapies for obesity are very expensive. On a large scale, our device could be made at a fairly profitable price," Srinivasan said in the press release. "I would like to see how it would transform care and therapy for people in global health circles that may not have access to some of the most sophisticated or costly options that are available today."

In the press release, the researchers said they were planning to investigate how to adapt the pill to stay in the stomach longer than the current period of 30 minutes, then to be wireless. They predict new ways of "developing" manufacturing, which could allow clinical trials in humans.

"Such studies would be important to learn more about the safety of devices, as well as to determine the best time to swallow the capsule before ... A meal and how frequency it should be administered," the statement said.

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