Researchers say that dementia vaccine could be on the horizon
Doctors hope, but some are also skeptical.
Right now, more than 55 million people are Live with dementia around the world, and 10 million new cases are diagnosed each year, according to Alzheimer's Disease International. If this is not alarming enough, this number should double every 20 years, with a planned total of 139 million cases by 2050.
But if the turning point to the future of dementia seems intimidating, there is also a cause of hope: several pharmaceutical research groups are currently testing vaccine candidates to help fight dementia . Read the continuation to find out how vaccines could help reduce the risk of dementia - even if approved vaccines could be in years - and why the best time to start preventing dementia is now.
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Routine vaccinations are associated with a lower risk of dementia.
Studies have shown that receive routine vaccinations As an adult, has been linked to a statistically significant reduction in the risk of dementia. In fact, a study in 2022 published in the journal Borders in immunology concluded that staying on the calendar of recommended vaccines during your adult years "can be an effective strategy for dementia prevention". However, they note that more research is necessary "to elucidate the causal effects of this association and the underlying mechanisms". AE0FCC31AE342FD3A1346EBB1F342FCB
The researchers analyzed 17 studies with a total of more than 1.8 million participants and found that vaccinations were linked to a 35% reduction in the risk of dementia. Although "all types of vaccination have been associated with a tendency to reduce the risk of dementia", they specifically noted that vaccines for rabies, tetanus and diphtheria and whooping (TDAP), Herpes Zoster , flu, hepatitis A, typhoid and hepatitis B were the most statistically statistical. important. "Individuals with more complete vaccination types and more annual influenza vaccinations were less likely to develop dementia. Sex and age had no effect on this association," wrote the researchers.
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Researchers are now working on targeted vaccines for dementia.
Now, experts are starting to develop vaccine candidates who, they say, could directly target dementia. Many of them use antibodies to help fight Alzheimer's dementia .
Several of these candidates for the vaccine have already participated in clinical trials at different phases and research stages. One of these candidates developed by the Vaxxinity pharmaceutical company Received the accelerated designation of the FDA in May this year. This could help speed up both the development and examination stages on the path of a patent.
Some are skeptical about the functioning of vaccines.
Although several companies participated in the race to produce the first dementia vaccine on the market, Some experts remain skeptical that these vaccines will be ultimately effective. "I predict that none of these therapies will significantly modify the course of the disease", " Karl Herrup , MD, professor of neurobiology at the medical school of the University of Pittsburgh, said Medical news today .
"Unfortunately, since the industry spent most of its resources on these approaches, sometimes ignoring or repressing other paths, it will take years before any significant therapy is available," he declared at the point of sale in November 2022.
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This is your best bet to prevent dementia while waiting.
Although vaccines can be in years - if they work at all - experts say that there are still means to reduce your risk of dementia in the meantime. "For the moment, the best approaches are non -pharmacological," explains Herrup.
In fact, Centers for Disease Control and Prevention (CDC) say that around 40% of all cases of dementia of Alzheimer and Dementia (ADRD) could be avoided or delayed Thanks to lifestyle interventions. "Since the ADRD takes years to develop, there are opportunities to develop and maintain healthy lifestyles that could reduce your risk of adrd or slow down its progression. It is never too late to break The old habits and create new ones, "they urge.
To start, you will want to strive with a healthy weight by exercising regularly and following a healthy diet like the Caisses regime in mind . Limiting your alcohol consumption and quitting smoking will help you reduce your risks, as is the treatment of underlying conditions such as diabetes, hypertension, hearing loss and depression, says CDC. Talk to your doctor to find out more about how you can reduce the risk of dementia, starting today.
