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WithFirst approved boosters In the fall of 2021, it's been a long time since many of us had our third shot. Fortunately, COVID showed a clear drop in the United States in the last month. According to disease control and prevention centers (CDC),infections have fallen With more than 28% of the last week, and hospitalizations also decreased by more than 27% at the same time. But the virus is unpredictable and there are some signs that anew variant could improve progress. Now, vaccine manufacturers as Moderna are preparing for this possibility.

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On March 17, Moderna announced that he hadsubmitted a request At the Food and Drug Administration (FDA), asking the Agency to modify its emergency authorization (EUA) to authorize a fourth shot of its CVIVID vaccine (mRNA-1273) for 18-year-old vaccinated adults or more. According to a statement by the pharmaceutical company, his request covers a second booster for all adults, regardless of the vaccine they received for their first.

"This submission is based in part on recent published data generated in the United States and Israel after the emergence of Omicron," said Moderna in his statement.AE0FCC31AE342FD3A1346EBB1F342FCB

Pfizer tooRecently asked the FDA To develop its UEA to allow another reminder on March 15, although its submission requests that the amendment covers adults over 65. But Moderna does not necessarily expect its submission to immediately translate to all adults.

"The request to include adults over 18 has been made of the flexibility of American disease and prevention centers (CDC) and health care providers to determine the appropriate use of a dose Additional reminder of ARNA-1273, including for those at higher risk of COVID-19 because of age or comorbidities, "said the company.

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Despite modernization and pfizer pushing an approval of the fourth dose, health officials are divided on the need for second boosters - a bit like they were initially intended for boosters in general. "I am a strong promoter to give a second booster now"Peter J. Hotez, PhD, a vaccine expert at Baylor College of Medicine in Houston, saidThe New York Times March 18th. "It's clear thatthe protection is zero now Fast enough a few months after your third dose. So it's short-lived. Hope is that a second booster restore it. "

But experts likeJesse L. Goodman, MD, a former Chief Scientist of the FDA, a question of how much this protection against the decrease affects the risk of hospitalization and death, that the first shot of recall had "formed a huge difference" in terms of strengthening Protection against, as noted hood.

"Although the protection is tired of light infections, without more information, we do not yet know to what extent, if any, protection against a severe disease," said GoodmanThe New York Times, adding that this is not clear "to what extent and how long another booster could help."

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