This medicine can raise a risk of cardiac attack up to 21%, the study shows
Research shows that a commonly prescribed drug can put your heart in danger.
Someone has aheart attack every 40 seconds of the US, according to theCenters for Disaster Control and Prevention (CDC). To live in the possibility, you could takeDrugs like aspirin, who have thought of reducing your chances of experiencing a cardiovascular event. But other drugs, although beneficial overall, can also increase the risk of a heart attack in some people. Recent research has found that a commonly prescribed drug can increase your risk of having a heart attack by up to 21%. Read it to know which medication may have about complications.
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Proton pump inhibitors can increase the risk of cardiac attack up to 21%.
A 2015 study published inPlos a highlighted the link between antacid drugs and heart attacks commonly prescribed. Researchers at Houston Methodist University and Stanford have examined health documents for nearly 3 million patients across the United States to determine if certain antacid drugs increase the risk of heart attack. According to the study, patients using proton pump (PPI) inhibitors have an increased risk of 16 to 21% heart attack compared to people who do not use this medicine.
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This risk is holding for people of all ages and health stories.
This risk is widespread throughout the general population, not just seniors or people with a history of acute coronary syndrome (ACS) that are more likely to have a heart attack, said researchers. This study has been one of the first to show a clear IPP risk for the general population, as previous research had health officials believing that the risk was relegated to a small subset of patients with a. Coronary illness and also used the anti-platelet. Drug clopidogrel to prevent future heart attacks.
"The investigators initially supposed that it was due to aMedicinal interaction Between these compounds and the FDA went so far as to release a warning about their concomitant use ", senior study authorNicholas Leeper, MD, Professor of Surgery at Stanford University Medical Center, explained in a statement. "It led us to use powerful" Big-data "approaches to try to determine if the PPIs could actually be associated with a risk in" All Venus ".
Researchers found no increased risk of heart attack with another antacidic drug.
Researchers say PPIs are mainly used for those with gastro-esophageal reflux disease (GERD). However, alternative drugs used to treat GERD may not have the same risk of cardiac attack. According to the study, researchers found that patients who used H2 blockers as an alternative treatment for GERD did not have an increased risk of having a heart attack. Unfortunately, doctors tend to use PPIs as the first line of defense of drugs in the case of GERD.
"Both drugs work by blocking and decreasing theGastric acid productionBut PPIs are considered stronger and faster in the reduction of stomach acids, "explained Healthline's experts when comparing PPIs and H2 blockers.
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Millions of people in the United States use PPIs.
According to the study, PPIs are widely used in the United States and around the world. Approximately 113 million IPP orders are met every year around the world and, to only 21 million people, about 21 million people had at least an IPP order in 2009, making it the third most high sold in the country. But the PPIs are not only available via the requirements: according to Medline Plus, there are many types of PPI-some of which areAvailable on the-counter(OTC), like Prilosec, Nexium, Prevacid and Zegerid. Researchers say OTC PPI sales associated with prescription sales are more than $ 13 billion around the world for this class of drugs.
"Our report raises concerns that these drugs, which are available on the counter and are part of the most commonly prescribed drugs in the world - may not be so sure that we previously supposed," Beeper said.
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