The alcohol of a side effect on the health of the brain, a new study says

New research has discovered that the brain plays a similar role in the treatment of alcohol than the liver.


In one season with ads without stopping onNew alcoholic beverages To try, a new study has made an important discovery on howwhile drinking can affect our brain. This comprehension throws the function of the brain into a new light in the treatment of alcohol and can lead to more modern methods to treat people who have an alcohol dependence.

For the study, which had just published in the newspaperMetabolism of natureResearchers at the School of Medicine at the University of Maryland have associated with the National Institute of Alcohol Abuse and Alcoholism to examine how the brain plays in the metabolization of alcohol .

Of course, it is well known that the liver is considered the key organ of the body's ability to deal with alcohol. The liver infringes alcohol in compounds, creating an acetaldehyde called acetaldehyde, known to produce altered speech, motor skills and reasoning to individual exposure when it is considered "drunk". Acetaldehyde then turns into acetate, which researchers refer as a "benign substance" which has not been considered previously considered a large part of the creation of these sedative effects.

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By using MRI scans for humans and mice, researchers have discovered ALDH2, an enzyme that converts acetaldehyde into acetate into thebrain. He appeared in the cerebellum (which controls balance and coordination), as well as the hippocampus, the amygdala and the prefrontal cortex - all the fields of the brain who play a role in decision-making and regulation emotions. When the Aldh2 enzyme has been singularly removed, the researchers said that "mice were resistant to the indunned motor deficiency by the consumption of alcohol".

Eat this, not that! Member of the HOWARD Grossman Medical Expert Council, Mr.D. Help us understand the importance of the conclusions. "It seems important because it has long been estimated that the metabolites of liver alcohol were what causes the effects of alcohol," says Grossman. "But now they find thatAlcohol actually works directly on certain areas of the brain that control things like awareness, coordination and impulse control"And that" metabolite acetate, seemed to be benin before, can also act differently in the brain. "

Grossman explains to win: "If the same phenomenon exists in humans and mice,This gives hope to find a way to block the effects of alcohol, both those we appreciate and those leading to dependence. If you could prevent people from feeling something from alcohol, it could seriously have a serious impact on one of the routes of dependence and dependency. "

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