Researchers discover 2 health measures that can reduce your death risk by 42%
They have a disproportionate impact on lifespan and health.
When you are young, it is too easy to take your good health for granted. After all, the vast majority of chronic diseases, from cancer to heart disease , are linked to chronological age.
However, medical researchers are exploring more and more to which age -related measures can have an impact on health and longevity . They say that the biological The age of your organs - separate from the number of trips you have made around the sun - could predict more precisely how long you live and in what condition.
This is because organic age offers a much clearer image of how our bodies are In fact Change over time. Rather than simply counting the number of years you have experienced, the biological age examines the functioning of your organs. Certain parts of your body can age more quickly or more slowly than others, and it turns out that some have an excessive influence.
In fact, a new study Published in the journal Nature Medicine noted that two biological age measures have an impact when it comes to prolonging and predicting both your lifespan and your health.
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Having a biologically young brain and an immune system is correlated with a longer lifespan.
More specifically, the study determined that people with young brains had a Risk of 40% death and those with younger immune systems had a 42% reduced risk . The subjects that had both a biologically young brain and an immune system have experienced the greatest protection against mortality.
The research team, led by Tony Wyss-Coray , PHD, professor of neurology and neurological sciences at the University of Stanford, analyzed blood samples of 44,498 participants in the British biobank, which were all between 40 and 70 years.
By measuring approximately 3,000 proteins found in the bloodstream, they evaluated the health of 11 major organs. They then used AI models to estimate the biological age of each organ as a function of these protein models. An organ was labeled "aged" if his biological age was higher than the real age of the person, and "young" if it were not the case.
Main author Hamilton Oh , PHD, recently said The study of the point of sale reveals that it was "definitively surprised" by the results of the research. The discovery of the team is particularly surprising that having young arteries not extend the life of subjects.
"I expected that many more organs are linked to longevity, but our data suggests that the immune system and the brain are essential," he said. “After having thought more about that, it has an intuitive meaning. The brain and the immune system control so many parts of our physiology - the brain through the nerve branches that grow in spinal cord and the immune system through the resident and migratory cells present in all tissues. "
For example, the authors of the study pointed out that having a young brain protects against heart failure and pulmonary diseases, in addition to dismissing more obvious conditions, such as dementia or cerebral vascular accidents.
"These systems can be the guards of our whole body," said Oh.
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Having aged organs can considerably increase the risk of death.
In subjects with several elderly organs, the risk of death has increased in particular. Having two to four elderly organs has been associated with a risk of death 2.3 times higher, while having five to seven elderly organs increased the risk by 4.5 times. Those who have eight or more elderly organs have seen their risk of death increase by 8.3 times.
"More than 60% of people with 8 extremely older or more organs of Blood Draw died within 15 years," noted the researchers.
When asked how everyday people can reduce the biological age of their organs, Oh stressed that additional research is necessary: "A major question is that young people in the brain and immune system really mean?" If we can understand this, we can find new ways to keep our brains and our immune systems young. ”
In the meantime, your best bet is to practice lifestyle interventions that promote overall health, brain health and a healthy immune system.
"Exercise, diet, sleep and low stress are experienced and real ways to live longer and healthier," advises OH. "A healthy lifestyle goes very far!"
