Good Lifestyle

Hypertension is mainly linked to unhealthy lifestyle factors, including excessive consumption of alcohol, smoking, a lack of exercise and a diet rich in fat and sodium. Alternatively, it could work in your family or be a sign of an underlying condition, such as Cronn syndrome. In a new research document, the doctors have shed light on a commonly unmatched condition which could be the reason why your blood pressure levels soar.

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Hypertension could be a sign of this underlying condition (and commonly not diagnosed).

Endocrine experts believe that between 5 and 14 percent of hypertension also have an unmatched primary aldosteronism, better known as Conn syndrome. According to their data, up to 30% of hypertensive patients in reference centers are faced with the same risk.

Overproduction of the Aldosterone hormone can cause high blood pressure. This hormone is responsible for regulating blood levels of sodium and potassium, explains Cleveland clinic . Hypertension is considered to be "the determining characteristic" of primary aldosteronism, although other symptoms can include:

• Fatigue
• Excessive thirst
• Frequent urination
• Headache
• Muscle cramps and weakness
• Blurred vision

Doctors warn that patients with primary aldosteronism fight against "significantly higher health risks", in particular linked to the heart, compared to hypertensive patients. Their results appear in a new clinical practice directive published on July 14 The Journal of Clinical Endocrinology & Metabolism (JCEM).

"People with primary aldosteronism face a higher risk of cardiovascular diseases than those with primary hypertension", "," Gail K. Adler , PhD, the main author of the newspaper of Brigham and Women’s Hospital and the Harvard Medical School in Boston, said in A press release . "With a low cost blood test, we could identify more people who have primary aldosteronism and ensure that they receive the appropriate treatment for the disease."

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People with CONN syndrome have an increased risk of heart and renal problems.

The proposed guidelines are the result of two extensive meta-analyzes which have evaluated more than 75 studies.

During the first meta-analysis, the authors evaluated the health files of 3,838 patients with primary aldosteronism and 9,284 patients with primary hypertension. They discovered that people with CONN syndrome have an increased risk of four cardiovascular conditions, an 8.8 -year median after receiving a diagnosis of high blood pressure.

The results were as follows:

• 2.58 greater chances of racing
• 1.77 greater probability of coronary disease
• 3.52 greater chances of atrial fibrillation
• 2.05 greater chances of heart failure

Another meta-analysis concluded that patients with primary aldosteronism have an increased risk of kidney disease and proteinuria. The authors reviewed the health cards of 6,056 people with primary aldosteronism and 9,733 with primary hypertension to calculate their results.

Here is what they found:

• 2.09 greater chances of chronic kidney disease
• 2.68 greater chances of proteinuria (high quantities of protein in urine, which can be a sign of kidney problems, diabetes or cardiovascular diseases)

In addition, the authors reported that people with primary aldosteronism "often report reduced psychological well-being and quality of life".

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Despite the increased risk of mortality, doctors do not regularly depress primary aldosteronism.

"Despite its prevalence and the serious risks for the health it poses, primary aldosteronism remains largely underdiagnosed and subcontracted," said the researchers.

But why?

According to Adler and his team, "screening for primary aldosteronism is extremely low, often delayed up to years after the diagnosis of hypertension" and "generally following the emergence of serious complications".

"Consequently, many people continue to be treated for primary hypertension, thus lacking targeted treatments or potential remedies, and hardening blood pressure in a subpoptic way and increased risks of cardiovascular and renal disease," they wrote in the document.

The morbidity and mortality caused by primary aldosteronism are "largely avoidable" with early screening.

The authors referred to the 2024 European Society of Cardiology (ESC) as an appropriate guidance test. According to their directives, it is recommended that All adults With diagnosed hypertension, it is also detected for primary aldosteronism.