How many people really go back after leaving weight loss, a new study reveals
Researchers examine the rebound effect after stopping Zepbound and similar medications.
Ozempic stormed the world in the past year, finding fame as the secret behind Hollywood Loss of weight loss . At the same time, several other similar weight loss drugs - Wegovy, Mounjaro and, more recently, Zepbound - began to get into the ranks. But although these drugs can promote weight loss, they are not miracle drugs. On the one hand, many patients reported Regarding side effects . Then, there is also the fact that weight loss drugs are intended for life use - which means that those who stop taking it will probably gain weight.
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Zepbound, an injection of shooting, is the most recent drug approved for " Chronic weight management "By the U.S. Food and Drug Administration (FDA). This month, it is officially available to be prescribed for adults with obesity or those who are overweight, according to a December 5 Eli Lilly. And now new research examines what will happen to patients when they stop using the drug, a common concern among all weight loss treatments. AE0FCC31AE342FD3A1346EBB1F342FCB
Eli Lilly sponsored the study, which was published on December 11 in the Journal of the American Medical Association . He followed 670 adults without diabetes who took the medication for 36 weeks. After that, half of the study participants continued to take Zepbound, while the other half was transferred to a placebo for another year.
During the second half of the trial, patients who continued to take the firing medication regularly continued to lose weight, eliminating an average of 5.5% of their body weight. Those who were gone to the injection of placebo, on the other hand, found an average of 14% of their weight that year.
The “overall reduction in average weight” for the total of 88 weeks was 25.3% for those who took Zepbound all the time, according to the study. It was 9.9% for those who took a placebo during the second half, indicating that they found some but not the weight they had lost after stopping treatment.
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"If you look at the magnitude of the weight gain, they Recover about half of the weight They had originally lost over a period of one year, "author of the main study Louis Aronne , MD, specialist in obesity medicine, and professor of metabolic research at Weill Cornell Medicine in New York, told CNN.
Arch admitted that on the basis of his experience, he thinks that it is probably that placebo people would continue to resume the weight they had lost during Zepbound.
"How long would it take? I do not honestly know," he said
But there are good news: it may not be the case for all those who leave the weight loss medication, according to Ark.
"It is not as if each person regained weight," he noted. "One in six, it looks like, is able to maintain weight loss without medication."
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