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In April, a strange model began to emerge in coronavirus mortality rates: in some places, men seemed to die from Covid-19 twice the rate of women. This fact has perplexed doctors and statisticians, inspiring research on theSocial and biological factors This could cause such disparity. This week, a new study published in the medical newspaperJama suggests a possible explanation:Men can be subject to more serious effects of COVID due to higher rate of genetic defects.

The SONDA study The cases of four coronavirus patients - two sets of families of families not related to the Netherlands - who have all been admitted to the ICU withSerious symptoms of the virus. According to the researchers, these subjects were selected because "in seriously affected young men, and in particular in the pairs of brothers (sharing half of their genomes, with an increased chance to identify a disease related to an X), a Unique genetic defect could present this could indicate a genetic predisposition to contract coronavirus infections. "

By using genetic sequencing and immunological tests, researchers have indeed identified rare genetic defects on the X chromosomes of subjects. They determined that these defects contributed to their serious cases by radically weakening the subjects "Immune responses (One of the four young men finally died of his condition).

Although the particular defects of the subjects are too scarce to account for the broader sex-oriented disparity in patient outcomes, they suggest that genetic variation can play a broader role in mortality rates related to the covidation of men. In particular, men have a copy of Chromosome X, while women have two. Many researchers concluded that this gives women a genetic advantage over men by lowering a womanChances of serious illness If at least one of the two chromosomes is healthy.

Although a study of four cases is substantially comprehensive, it opens the door to additional research on the subject of how genetic factors influence the severity of cases andPatient results When it comes to coronavirus. In the end, it can help remedy the question of why men of young healthy men fall dangerously sick and emphasizeNew treatments This could save countless lives. And for more factors that influence the results of the patients, read on the4 symptoms of coronaviruses most likely to be fatal.