A new study warns that home DNA kits often do not manage to detect certain breast cancer genes

It turns out, 23andy comes with a huge asterisk.


DNA kits at home have become incredibly popular these days. Want to know more about your ancestors? Cotton-rod onAncestrydna. Seeks to find thebest way to lose weight Based on your genes?HOMEDNA You have covered. But if you thought that the sending of a saliva sample could determine if you are more at risk ofbreast cancer Or not, think again.

Researchers of the Genetic Information SocietyInvited examined the Test of the BRCA of 23andm, which claims to test three common variants in the BRCA1 and BRCA2 genes indicating an increaserisk of breast cancer. But researchers have found that the company's home test is missing nearly 90% of cases. When the authors of the study have requested more than 4,700 patients with a known BRCA1 mutation or BRCA2 to take a home test, only 12% received positive results. The other 88%? Their mutations fell in the 1000+ that 23andy does not test.

23andy home mutation tests have long beencriticalBut the study of Invitae-presented this month at the American College of Medical Genetics and the annual genomic meeting - is the first to show how limited.

Although the 23andy BRCA test is authorized by theFederal drug administration, the organization warns that "a negative result does not exclude the possibility that a person has other Mutations of the BRCA that increasesRisk of cancer. "They also claim that the test results" should not be used as a substitute to see your doctor forCancer projections. "However, many consumers simply receive a negative result and think they are clear.

"People are entitled to their own genetic information, but with this right comes a responsibility"Dr. Robert C. Green, a teacher at Harvard Medical School, told theNew York Times. "If you go around the medical current, read the warnings."

23anda responded to the study, calling for many interpretations of the conclusions of "misleading".

"Helping people understand that their genetic information is core to our mission and we are very clear with our customers that our BRCA1 / BRCA2 report only tests three thousands of genetic variants in these genes", "Jeffrey Pollard, MD, the Director of Medical Affairs of 23andy, stated in a declaration. "23andy tests for these variants because they are three of the different risks associated with breast and ovarian cancer. ... As part of the FDA review process, we have demonstrated that our test is greater than 99 % analytically accurate for the genetic health risk reports we provide. "

And if you are worried about your risk of breast cancer, check these40 ways to prevent breast cancer after 40.

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Categories: Health
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