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It appeared for a moment that we were beyond the worst of the pandemic, but the situation of the United States has evolved dramatically in the last two weeks and hospitals across the country are again flooded with covidant patients. On July 23,Coronavirus hospitalization rate increase in 45 states, depending on the data of theThe New York Times. And while the vast majority of thesePatients are unvaccinatedIt's not necessarily true for all. Disease and Prevention Control Centers (CDC) reports that the more than 159 million people had been fully vaccinated from July 12, when they collected the data nearly 5,500 werehospitalized with COVID In the United States, it is only 1003% of the entirely vaccinated people who get serious COVIDs, but new research show that half of them share an interesting commune.

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A study published on Medrxiv earlier this month, which has not yet been examined by peers but has been funded by the CDC, examined the effectiveness of Covid vaccine in preventionHospitalizations related to viruses In the United States, researchers analyzed 1,210 US adults in hospitalized between March 11 and May 5, comparing positive cipid-positive patients with patients who have been tested negative for the virus. According to the study, nearly half of infected hospitalized patients after being vaccinated were immunocomized. Of the 45 patients with revolutionary covidation infections, 44.4% were immunosuppressed.

"All patients who have been fully vaccinated that I admitted to the ICUhave been immunocomized. Each of them,"Rice Todd, MD, co-author of the study and director of the medical intensive care unit at the Medical Center at the University of Vanderbilt in Nashville, in Tennessee, told NBC News this week. He added that all other hospital covidant patients have not been vaccinated.

A study published in the medical newspaperClinical microbiology and infection earlier this month in the same way as152 Serious breakthrough infections In Israel, 40% involved immunodezing persons.

Rice and its team also confirmed that the effectiveness of vaccination was lower in immunosuppressed patients. According to their data, vaccines were 86.9% effective in preventing covid hospitalization overall, but only 59.2% effective in immunocompromised patients.

"Immunosuppressive conditions affect millions of adults in the United States," says the study. According to the CDC Advisory Committee on Immunization Practices (ACIP), immunocompromised persons account for about 2.7 percent of the country's population and includes those with a strong tumor and hematological malignant tumors, HIV, immunodeficiencies. Serious primers have received a solid organ or hematopoietic cells cell transplant or take immunosuppressive drugs.

Another great study published in the medical newspaperCancer cell In June determined to determine how COVID vaccines are effective for cancer patients. The results showed that, although most cancer patients of the study have responded well to fire, 30% of theseImmunosuppressive had no antibody production in response to their vaccine.

These results add to the editing evidence that about six million people in the United Statesdrugs that remove their immune systems-Who includes not only those with cancer, but also people with arthritis, psoriasis and those who haveOrgan transplants received-aredo not have strong reactions to their Covid vaccines After two doses.

The authors of the new CDC study concluded that "future work is needed to understandEffectiveness of the vaccine Among people with specific immunocompromization conditions and the sustainability of the protection of this population to inform the need for recall vaccines and / or preventive non-vaccine interventions, such as the use of the mask and distancing social. "

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It is looking for this kind that led the ACIP to meet on July 22 to discuss whether immunocompromised persons or notNeed a third shot To combat their higher rate of serious revolutionary infections.

The Committee cited the CDC study in its meeting notes and also referred four smaller studies that showed that 16 to 80% of people with weakened immune systems did not develop detectable antibodies against COVID after having got their doses of recommended vaccines. But among those who had no answer to their initial blows, 33 to 50% developed antibodies after a third dose.

"Emerging data suggest that an additional COVID-19 vaccine dose in immunocompromised people improves the antibody response and increases the proportion that responds," concluded ACIP in their presentation. However, the CDC has not yet been officially recommended that health care providers give immunosuppressed people a third dose of Covid vaccine.

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