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Like the coronavirus itself, the vaccine that protects against Covid-19 can affect everyone differently. Some people haveno side effects, others are stuck in bed for a few days. And while some peoplebuild strong immunity After having their blows, others are not so lucky. Although it is difficult to predict how you react, medical experts warned thatPeople with autoimmune disorders Or those who take immune suppressors may not have a robust answer. And now, a new study revealed that a group of people tends to have particularly reduced immunity after being vaccinated. In fact, half of them havenoantibodies after their vaccination.

A study of May published in theAMERICAN MEDICAL ASSOCIATION JOURNAL found that 46% ofTransplanted patients who have had two doses The Moderna or Pfizer vaccine produced no CVIV-19 antibodies, the key vaccine indicator was effective or not. The good news is another 40% of the 658 patients transplanted studied had no antibodies after their first vaccination, but developed antibodies after their second shot. However, this still leaves a significant percentage of patients without any protection against COVID.

"It's really much more a crucial contrast than expected"Dorry Segev, MD, a transplant surgeon of Johns Hopkins Hospital, told CBS News. "I hear a transplant and othersImmunosuppresse people who have been vaccinated and relaxed their safety behaviors and are now admitted to hospitals and some die because they get COVID-19. "

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Similarly, April's research of the Mayo clinic, published in theAmerican Journal of Transplantation, also raised the concern that transplanted patients seem to have aReduced immune response Covid-19 vaccine. The small study examined seven recipients of an organ transplant diagnosed with COVID-19 at the Mayo Clinic in Florida after obtaining one of the mRNA, Pfizer or Moderna vaccines. Two patients had received a dose and five were fully vaccinated. Five of the patients were hospitalized, three of which required oxygen after being discharged. Only one of the patients had antibodies against Covid. The research team therefore estimated that the vaccinated solid organ transplantation rate is 10 times higher than the general population.

"This study isOpening of the eyes for the Community of Transplants"Principal ResearcherHani Wadei, MD, a nephrologist Transplant center of the Mayo Clinic, said in a declaration. "Our study suggests that transplanted patients do not have the same immune response as the general population. They have been infected after being vaccinated and raising protective measures, thinking that they were safe from the virus."

Wadei added: "Care should always be implemented in immunocompromised patients of solid organs vaccinated until we have better vaccine strategies. ... All persons, especially transplanted patients, should continue to follow protective measures, such as social distancing, mask wear and ordinary hygiene. "

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Another study, published earlier this month in the newspaperAnnals of rheumatism diseases,Looked two groups of people vaccinated against COVID-19: 84Patients with autoimmune diseases (like rheumatoid arthritis, inflammatory intestinal disease, psoriasis and certain types of arthritis) and 182 healthy participants. In the latter group, all but one of the patients developed antibodies against COVID-19. In the first point, as much as 1 in 10 people failed to develop antibodies.

In particular, research has shown that patients taking as methotrexate (sold like RheuMatrex, Trexall, Otrexup, Rasuvo) and Rustimab (Rituxan) for theirAutoimmune diseases respond badly At the vaccine, WebMD reports. Indeed, these drugs suppress the immune system so that the disorders, which cause your immune system are too active.

As Wadei, sickness and prevention centers (CDC) warnedPeople with compromised immune systems, including those with organ transplants, should continue to wear masks even if they are fully vaccinated. "If you have a condition or take medications that weaken your immune system,You can not be completely protected Even if you are fully vaccinated, "reads the CDC guidelines, which have been updated in mid-May." Even after vaccination, you may need to continue taking any precautions. "

CDC DirectorRochelle Walensky, MD, developed on this orientation during an appearance on the NBC Meet the press May 16th. "We know that - and there are emerging data to suggest - that if you do not have a fully competent immune system of chemotherapy, transplants, other immune modulating agents than the The vaccine may not have worked For you, "she says." So, please, before taking off your mask, consult your doctor. "

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