Why some become bad Covid and others have not discovered
Two Histument studies have identified how Covid moves around our immune response.
With more than 200,000 Covid-related deaths in America, it is clear that the virus is sneaky, passing around our immune systems like a bicycle messenger during rush hour. But why are some people far, much more sick than others? "From the first months of the Pandemic of Covid-19, scientists disconcerted by the ferocity of the disease have wondered whether the fighter of the virus of the avant-garde, a molecular messenger called type I interferon, lack of action in some serious cases. Two articles published online inScienceThis week confirms that suspicion. They reveal that, in a large minority of patients with severe Covid-19, the interferon response has been applied by genetic defects or malchored antibodies that attack the interferon itself, "reports reports.Science. "Together, these two documents explain nearly 14% of severe CIVID-19 cases. It's quite surprising, "says Qiang Panhammarström, immunologist at the Karolinska Institute. Read it to see how it concerns you and to ensure your health and health of others, do not miss theseWithout signs that you have already had coronavirus.
Patients have a "response interferon altered"
Scientists have studied a series of brothers who have sick with COVID - some died. "The common thread of research is the absence of a substance called interferon that helps orchestrate the defense of the organization against viral pathogens and can be infused to treat conditions such as infectious hepatitis," reportsBloomberg. "Now, increasing evidence suggests that a significant minority of CIVID-19 patients is very ill because of an interferon response with impaired faculties. Twin Studes of historical published Thursday in the newspaperScience has shown that insufficient interferon can hide from a dangerous turn of SARS-COV-2 infections. "
"It looks like this virus has a big turn," said Shane Crity, a professor in the center of infectious disease and vaccine research at the Jolla Institute for Immunology in California. "This great thing is to avoid the initial innate immune response for a significant period of time and, in particular, avoid an interfering response of type-1 at the beginning of 1."
"There has never been an infectious disease explained at this level by a factor in the human body. And it is not an isolated cohort of Europeans. Patients come from all over the world, all ethnic groups," said Co-author Isabelle Meyts, an immunologicist pediatrics to the Louvain University Hospitals, who "was struck by an article on the fact that the antibodies of thugs underpinning Covid-19 out of 10% of severe patients" reports "Science. "Another conclusion, that 94% of patients with interferon attack antibodies were men, also helps to explain why men face a higher risk of serious illness."
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If early identified, lives could be saved
If scientists can identify this issue early and interfere quickly, lives could be saved.
"" We believe that the timing can be essential because it is only at the beginning of the early phase can really fight the virus particles and defend against the infection "Alexander HoischenHead of genomic technologies and the immuno-genomic group at the Medical Center of Radboud University in Nijmegen who analyzed the DNA of the two sets of brothers, "Bloomberg said. As to keep you and stay free of Covid-19, before it strikes,mask, avoid crowds, wash your hands and do not miss these35 places you are most likely to catch Covid.
