Good Lifestyle

Year2019 will be recalled for a lot of things, ofGame Of Thrones"unsatisfactory final at the birth ofPrince Harry andMeghan Makle's first child. But while pop culture and politics tend to dominate the landscape of the last year, if you arelive with a chronic illness Or if you are close to someone who is, you will remember 2019 for his alternating life - and in some cases, safeguarding lifemedical breakthrough. The new treatment of prostate cancer at a pill for peanut allergies, read more about some of the most promising medical advances we've seen in 2019.

This year, scientists broke a major plot with a potential technique for dealing inherited diseases such asAlzheimer, alcoholism, hypertension, anemia of the sickle, ADHD andautism.

In October,Harvard scientists and mit Unveiled a new way to edit genes called "Main Modification". In an interview withNPR, chemist and biologistDavid Liu, one of the researchers of the technique, loved by the main publishers at "word processors [which are] capable of searching target DNA sequences and to replace them accurately." Essentially, he says, it's the genetic equivalent to make a "find and replace" in Microsoft Word-and could potentially correctup to 89% Genetic defects causing disease.

In October 2019, the American Gene Therapy Society (AGT) filed aApplication with American food and drug (FDA) seeking to launch a human trial for what he believes is an expected anticipated remedy for HIV. Whena person is infected with HIVIt deactivates the T cells of this person - the immune cells that are responsible for combating the virus. AGT therapy, currently passing through the nameAGT103-T, involves extracting these damaged T cells, genetically modifying them to restore their immune function, and then returning to the patient in order to fight the virus.

In 2019, anti-aging researchers from the WYSSS Institute at Harvard University for biologically inspired engineering increased considerably in the search for young eternal. Researchers, including the renowned antimuridic expertGeorge Church, PhD, published a study in the newspaperActs of the National Academy of Sciences in which they have shown that this could be a possible day ofSlow or reverse aging Using gene therapy to reprogram the cells.

In the study, the Church and its colleagues have equipped viruses with programmed genes to make various proteins related to the prevention or inversion of four age-related diseases: obesity,Type 2 diabetes, renal insufficiency, andcardiopathy. They then have "infected" mice with the viruses, which charged the mouse's liver to produce the aforementioned proteins and secure them in the blood. TheresultsWeight loss in obese mice, reversal of diabetes in diabetic mice, reduced renal atrophy in mice with renal fibrosis, andIncreased cardiac function In mice with heart failure - suggests a future where youth and longevity are just injection.

Biotech Company Biogenannounced in October That it seeks FDA approval for a new drug called Aducanumab. The therapy targets amyloid beta, a protein that accumulates in the brains of people with Alzheimer's disease and that it is thought to play a role in the disorder.

Inclinical tests, Alzheimer's patients are treated with experienced trivialsImproved memory As an increased capacity to participate in daily activities, such as the conduct of personal finances, the execution of housework and travel independently outside the house. If approved, Aducanumab would become the first therapy to reduce the clinical decline of Alzheimer's disease and the first to demonstrate that the elimination of amyloid beta produces positive clinical outcomes for Alzheimer's patients.

The54 million Americans who suffer from osteoporosis or other weak bones received good news in April when the FDAapproved a new drug called FAILURE. Designed to treat osteoporosis in postmenopausal fracture women, the drug is the first and only one of its kind, not only does it reduce bone loss, but it can also help build new bones.

In case of asthma attack, the inhalers can be rescue - but only if they are used correctly. To make sure they are, Teva Pharmaceuticals created what he says is the world's first and only digital inhaler in the world with integrated sensors that connect to a mobile application to provide appropriate use information for people. asthma and COPD.

The device, called theProAir Dighaler, has receivedFDA approval In December 2018 and became available in 2019. Whenever a patient uses, the device measures and saves data that can be used to ensure the correct use of the inhalers.

At2019 Annual Meeting of the American Society of Clinical Oncology (ASCO), researchers presented the results of aclinical test In which they studied the effects of Olaparib drugs on men with prostate cancer. The drug aims and inhibits an enzyme that cancer cells need to grow. The results? The oral drug, which is already approved to treat breast and ovarian cancers, delayed the progression of prostate cancer in 80% of men with a specific mutation type.

"Even though the men of the trial had advanced, the prostate cancer strongly pretreated, Olaparib delayed the progression of the disease in these patients for a median of 8.3 months, with 35% without progression since more than one An "according to a report of the ASCO.

The Olaparib drug showed as many promises for the pancreas in 2019 as for the prostate. In June, researchers published the results of ainternational drug test Test of the efficacy of Olaparib in people with metastatic pancreatist cancer, a form of late-phase disease that has a five-year survival rate of less than three percent. In the process of the drug, called thePancreas Test Olaparib Cancer Cancer (Polo), the duration of time a patient has lived with the disease without it being empire was twice as long as those treated with Olaparib because they were for those treated with a placebo: 7.4 months by Report to 3.8 months.

Although this is theCause of Cancer Death Cause In women, the lethality of cervical cancer hasdecreased significantly Thanks to Routine Pap smears. But a study of April published inBMJ Open This will facilitate potentially that it is even easier to be projected for cervical cancer. Although more tests are needed, researchers at the University of Manchester have concluded that simple and non-invasive home urine tests can be just as effective when screening for cervical cancer as smear.

Breast cancer is now theMost common cancer for women. Screening thereof is usually done with a mammogram - but like smear dad, these can be uncomfortable, not to mention expensive. Fortunately, a group of British researchers might have found a way to test for breast cancer without mammograms. In their study presented at theCancer Conference of the National Cancer Research Institute 2019, Scientists from the Nottingham University have shown that a simple blood test could be able to detect breast cancer in women up to five years before becoming symptomatic.

In October, theFDAApproved a new drug to treat cystic fibrosis. Called Trikafta, target drugs various gene mutations that are collectively responsible for 90% of cystic fibrosis cases. In those with these mutations, the body produces a defective protein that constitutes the source of the complications of cystic fibrosis. Trikafta helps defective protein function to mitigate the symptoms of cystic fibrosis. For more than30,000 people living with cystic fibrosis in the United States.Trikafta is the first medicine that can treat the underlying cause of their disease.

Although peanut allergies can be fatal, there is unfortunately no treatment approved by the FDA for them. But that could soon change: in September, aFDA Advisory Committee recommended that the Organization approvesPalforziaOral immunotherapy that administers small daily doses of peanut proteins to children and adolescents with peanut allergies.

The dosage, which gradually increases over a period of months, is designed to strengthen tolerance in the immune system, reducing the frequency and severity ofAllergic reactions. As a result, people who may have already had a dangerous reaction to peanuts should be correct if they are accidentally explained.

These days, the FDA approves only drugs and medical devices. With the rise of artificial intelligence, it tooApproves computer algorithms This can be trained to make accurate diagnoses using medical images.

In 2018, the FDA approved23 AI algorithms For use in medicine, and the organization continued to approve new algorithms in 2019. One of the most recent solutions for a sign of the FDA was theCritical Suite of GE Healthcare. Approvedin SeptemberIt uses Ai to scan X-ray images and detect collapsed lungs, a fatal condition that affects approximately 74,000 Americans each year.

Researchers atColumbia University Closer closer to patients with chronic respiratory diseases this year where they used transplanted stem cells to successfully cultivate new lungs in mouse embryos. As detailed in a November document published inMedicine of nature, scientists have decided to take advantage of the innate ability of the mouse embryos to cultivate organs on their own implant donor stem cells that are then transformed intoFully functional lungs. This research proves that in the future it might be possible to use animals to generate new healthy lungs for humans.

In September,BioLife4d became the first American company to3D Print a human heart With the exact structure of a normal size core and many same functions. It is an important step towards the ultimate goal of the company: human hearts of the size of a size 3D-print that can be used by surgeons in grafts and pharmaceutical companies for safer and faster tests of new cardiac therapies.

In October 2019, researchers at the State University of Georgia revealed that they had discovered theFirst effective and non-invasive method To detect and diagnose liver diseases in early phase. Their method uses a new dye in MRI tests known as proca32.collagen1 that targets collagen overexposure in people with liver disease in early phase. Compared to conventional contrast agents, ProCa32.Collagen1 is twice as accurate and can detect tumors 100 times smaller. It also requires a much lower dose, making it safer for patients.

One of the drugs approved by the FDA in 2019 wasNOVO-TTF100L, the first new treatment of mesothelioma of more than 15 years. According toColin Ruggiero, a health writer toMesothelioma.comNovo-TTF100L is a portable device that uses electrical fields suitable for specific frequencies to disrupt the division and growth of cancer cells. In a clinical trial, the median survival rate for patients treated simultaneously with Novo-TTF100L and chemotherapy was about 18 months.

Although an anti-tuberculosis vaccine (TB) existed since 1921, it is only effective in babies and children. In October, however, GlaxoSmithKline (GSK) researchers announced significant progress to develop an indispensable anti-tuberculosis vaccine for adults.

Inclinical tests This took place in three African-Kenya countries, South Africa and Zambia - the vaccine prevented tuberculosis in about half of the people who received it. Although it only works half of the time, the vaccine could save millions of lives. "These results demonstrate that for the first time for almost a century, the world community potentially has a new tool to help protect against tuberculosis"Thomas Breaver, MD, Chief Medician of GSK vaccines, said in a statement.

Although most medical advances are the product of the new science or new technology, some stem from improved policy. This is the case withTelementation health, Aka online therapy, which has gained a major traction in 2019 thanks to a combination of technology and politics.

"The growth of telehealth in theMental Health Space is a relatively simple, innovative, cost-effective way to respond to the epidemic of rising mental health problems, "Rahul Mehra, MD, explains. In July 2019, his organization, theNational Performance Health Center (NCPH), establishedECARE4KIDS, a tepouse program servingpublic school children in Florida.

But they are not only children or Floridians who see these progress. A October study by law firm on health careEpstein Becker Greenshowed that the 50 states now provide a certain level of Medicaid coverage for telehealth services. Even the congress sees the advantage: in February, he introduced the Law on the Expansion of Telemedicine of Mental Health , which, if passed, will allow all Medicare beneficiaries to access telemental health services at home.