That's why half of the population is more at risk of coronavirus

The researchers found that Covid-19 is the most dangerous for men.


Six months after the coronavirus which causes Covid-19 is first known, we have seen the heavy tribute that he has taken on the world. The deadly disease has killed nearly 400,000 people on a global scale, including more than 110,000 people in US scientists study who is most at risk, in order to find solutions to slow the spread. But a major breakthrough is dark: the men, a group that is half of the population, haveThe highest coronavirus mortality rate.

In the region of Lombardy of Italy,Men included 82% of patients In intensive care units (ICUS), according to an article published in theAMERICAN MEDICAL ASSOCIATION JOURNAL. And in New York, the biggest Hotspot of Covid-19 of America, abouttwice as many men died that women, according to the epidemiological data of the Department of Health of the City.

Why is it? Well, the answer lies in their genetics. Androgens (male sex hormones Like testosterone) increases the ability of the virus to divert healthy cells.FARANAK FATTAHI, PhD, a stem cell biologist at the University of California, San Francisco, studied the data of hundreds of male patients in the United Kingdom Biobank and found that the most active androgens they had in their blood, themore serious their cases of COVID-19 were. (This study, which has not yet been examined by peers, has been published bybiorxiv.)

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This proof is also inspiring possible treatments. For example, researchers around the world test androgen-privation (ADT) - drugs that cut testosterone levels, usually used to combat prostate cancer - to see if it decreases the risk of coronavirus. The results so far are promising. In a study published inAnnals of oncology,Andrea power, MD, responsible for molecular oncology at the University of Lugano in Switzerland, found that cancer patients on ADT wereA quarter as likely to contract COVID-19 Compared to those who are not on ADT.

However, other medical experts, think that women could be the key to the puzzle because they have a greater chance to survive the coronavirus.The New York Times reported that Los Angeles scientists and Long Island, New York, hold clinical trials in which theyGive doses of female sex hormones-Bas like estrogen and progesterone - to increase their immune systems. Researchers say they believe that progesterone will have the greatest impact because it contains anti-inflammatory properties.

Sara Ghaandehari, MD, a pulmonologist and an intensive care physician at Cedars-Sinai in Los Angeles who run the study of progesterone, saidThe New York Times"There is a striking difference between the number of men and women in the intensive care unit and men aggravate clearly." And for more ways Coronavirus is dangerous for men, discoverThe shocking reason older men are at an even higher risk of coronavirus.

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