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With a handful of vaccines on the market around the world, the opportunity to get two different shots can have crossed your mind. And you are not alone: ​​the researchers think that the combination of two vaccines could be the key toreinforce immunity In some recipients. A recent study sought to discover the effect of mixing two vaccines, Pfizer and Astrazeneca, the latter which is not currently approved in American researchers concluded that the administration of a dose of Pfizer after a dose of Astrazeneca has considerably improved the immune response.

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The study, which was discussed in an online presentation on May 18, revealed that give aPfizer shot after a stroke of astrazeneca Immunity "greatly improved". Carlos III Health Institute's combivac clinical trial examined 663 people who received a photo from Astrazeneca followed by a Pfizer shot and a control group that received no return. The control group has no change in antibody levels, while those who received Pfizer - at least eight weeks after their initial AstraZeneca obtained a more powerful immune response.

The AstaZeneca vaccine is a vector vaccine at a viral vector dose, similar to the Johnson & Johnson vaccine that has been approved for emergency use in the United States, the shake that Pfizer has given the immune response to the recipients of Astrazeneca leads to much higher antibodies than they were before. had. AsNature Notes, these are the results that the researchers had hoped.Zhou Xing, PhD, an immunologist at McMaster University, saidNature that theAntibody response For the Booster Pfizer seems to be stronger than people usually have after two doses of the Astazeneca vaccine, based on previous data. However, it is currently difficult to know how the antibody response compares to a person who has received two doses of Pfizer or Moderna vaccines.

According toNatureMixing vaccines in this way - known as the first heterologous and Boost - is a strategy that has proved effective against other diseases such as the Ebola virus. A handful of European countries has begun to recommend to people who have received the vaccine against Aspaazeneca get a second dose of a mRNA vaccine (such as Pfizer or Moderna) in the hope of triggering a stronger immune response. According toNatureThe double doses of the AstaZeneca vaccine do not seem valid because viral vector vaccines tend to become more and more efficient over time.

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It should be noted that mixing two different vaccines couldresult in more side effects, according to a study published on May 12 inThe lancet. Researchers have found that people who have received mixed vaccines were more likely to report light and moderateSide effects, including headaches, chills and muscle pain.

While the disease and prevention control centers (CDC) do not yet advocate the combination of vaccines, saying "the two doses of the series must be completed with theproduct", the agency could change its recommendation because more studies are completed.

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