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The blows of Pfizer and Moderna Covid have beenswivel vaccines in the USA.' race to end the pandemic. More than 85 million people in the countryhave been completely vaccinated With Pfizer and 62 million Moderna, according to the latest data from Centers for Disease Control and Prevention (CDC). Nevertheless, a small number of these completely vaccinated people are still being infected by Covid, as a number of factors like the rapidDelta variant propagation-Have the effectiveness of both vaccines. Today, the search has found a common condition that can also reduce your vaccine protection if you have received one of these shots.

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The study, which was published on July 13 inJama Internal Medicine, Sought to know how much the protection of the two approved mRNA vaccines givePeople with cirrhosis. Cirrhosis is severehealing of the liver which can be caused by many forms of liver disease and other affections such as hepatitis and chronic alcoholism, by the Mayo Clinic.

The researchers of the study analyzed more than 20,000 people with cirrhosis who received a lease at dose to be Pfizer or Moderna and compare their experience to more than 20,000 patients with cirrhosis that are not vaccinated. According to the study, a dose of an mRNA vaccine is only 64.8 percent effective against COVID infection and two doses is 78.6 percent effective against infection.

CDC reports thanThe Pfizer vaccine is usually 95 percent effective against infection after two doses based on evidence from clinical trials. Moderna, on the other hand, is 94.1 percent effectiveAfter two doses In the general population based on evidence from clinical trials. This means that these vaccines are a little less protection in people with cirrhosis, concludes the study.

But the effectiveness against hospitalization or death was still high for patients with cirrhosis. According to the study, both one and two doses of an mRNA vaccine have been associated with a 100 percent reduction in Covid hospitalization and death for patients with cirrhosis. Nobody in the vaccinated group died of Covid, but there were two Covid deaths in the unvaccinated cirrhose group.

"Patients with cirrhosis that could vaccinatedAlways get the infectionBut they are unlikely to die or hospitalized Covid-19, "the main author of the studyBinou V. John, MD, Associate Professor affiliated with the University of Miami Miller School of Medicine, confirmed in a statement.

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Cirrhosis Having is also likely to delay your response to the vaccine. According to the study, there was no noticeable difference between vaccinated and non-vaccinated cirrhosis groups after the first 28 days after the first dose. It was only after these 28 days that the efficiency of 64.8 percent against the infection and efficiency of 100 percent against hospitalization or death.

"The difference begins in 28 days. It's when you start seeing the number of cases in the vaccine group and more in the non-vaccinated group, "says John. He added that clinicians who work with patients with cirrhosis may want to warn them about their immune protection.

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