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To get vaccinated Gives us protection against Covid, but everyone does not exercise the same sense of security because research suggests that the effectiveness of vaccines may vary. Pharmaceutical companies producing Covid's plans excluded people who wereTake immunosuppressive drugs Clinical trials, scientists still do not know how current the current vaccines work for these people. The experts currently rely on emerging research to determine how people taking immunosuppressive drugs at COVID tariff after being fully vaccinated and the news may not be good for millions of American adults. Recent research estimate that nearly six million Americans take immunosuppressants who could reduce their vaccine response.

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A study published May 20 inJama Open Open NetworkData analyzed for American adults from 18 to 64 years from January 2017 until December 2019 using Clinformatics Data Mart, a database of national commercial demands of more than three million Americans, to see how much oftook immunosuppressants.

Beth Wallace, MD, the corresponding author of the study and a rheumatologist with the Medicine School of the University of Michigan, told CNN only by his research, she considersSix million Americans Let us currently take immunosuppressants who could reduce the response to the vaccine. Wallace noted that this is probably a conservative estimate because his study did not include people on Medicare.

Unfortunately, several studies have recently shown that people on immunosuppressants can have a reduced vaccine reaction. May 5Jama Study led by a team of researchers from Johns Hopkins Universityanalyzed the vaccine response With more than 650 recipients of an organ transplant who took medication to suppress their immune system and found that 46% had no antibody response after two doses of Pfizer or Moderna.

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Another study of the University of Washington Medicine School - Preprinted on April 9th ​​on Medrxiv analyzed nearly 200 patientswith various conditions Such as lupus, psoriasis and syndrome of inflammatory stool, and found that two particular immunosuppressive drugs (glucocorticoids and cell depletion agents B) "substantially" vaccination vaccine including immunity to the covidation of vaccines. MRNA.

"Nobody really anticipated the vaccine responses would look so bad," "Kathryn Stephenson, MD, a specialist in infectious diseases and assistant professor at Harvard School of Medicine who were not involved in any of the three studies, told CNN.

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This may not say that individuals taking immunosuppressants are not protected, however. Experts do not know exactly how the vaccine response is correlated with protection against Covid. The US and Drug Administration (FDA) and Disease Control and Prevention Centers (CDC) advises patients againstTake tests to check For antibodies as a result of vaccination, as the results may not accurately determine someone's protection level.

"For patients who do not have an antibody or do not produce a robust antibody response, we do not know yet if you will be protected," said Leukemia and Lymphoma explained to CNN in a statement. "There are other types of immunity that can protect. Immune cells called T cells can play a role in the ability of our immune system to protect us from COVID-19."

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