That's what it means that if you have Pfizer and had no side effects, a new study indicates

A new study examined the connection between the side effects and the antibody response in the recipients of Pfizer.


Physicians and public health experts spent a lot of time at the beginning of the deployment of Covid vaccineswarning that side effects had to be expected. And while it was reassuring to know that fever, fatigue and other lightweight reactions were not worrying, what many of us did not realize were a lack of side effects of vaccine Nor was the reason for ringing an alarm. "When you really examine the [clinical] test statistics,Most people did not have any side effects. Just over 50% did not experience side effects at all: "Thaddeus Stappenbeck, MD, President of the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute, explained on the hospital website. But because it was not widely known when people started to leave their vaccination centers feel good, they started worrying whether the vaccine worked or not. In the last seven months, experts have tried to send the message that while side effects are a sign that your vaccine works,no side effects are not a sign that this is not the case. And now, a new study of the Infectious Disease Clinical Research Program (IDCLP) devotes a light on what it might mean, especially when it comes toSide effects and vaccine against Pfizer.

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A team of doctors and scientists in uniform services from the University of Health Sciences, the Naval Medical Research Center and Henry. Mr. Jackson Foundation for the advancement of military medicine met to show how someone's immune response who had no side effects differs from that of someone who had strong. In their study, which was posted on the Pre-Printed Medrxiv website on July 2 and has not yet been examined by peers, the authors explain that they wanted to examine the connection because of all the assimilated confusionSide effects and efficiency.

"During the deployment of COVID-19 vaccines, it became common that the media and health professionals are common to say that the presence of symptoms means that a vaccine is" working ". Although this statement is fundamentally true because "works" vaccines by inducing inflammatory responses, this also implies incorrectly thatLack of post-vaccination symptoms May indicate a lack of appropriate antiviral antibody responses, "wrote the authors.

Your immune response to a virus or vaccine is measured in various ways, but one of the most common is the production of antibodies. The antibodies are "specialized proteins produced by the immune system identify and destroy foreign invaders, such as bacteria and viruses, "A blood test as an antibody is performed to determine the (qualitative) presence and (quantitative) quantity of antibodies in the blood. "

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To conduct their study, the research team tested 206 employees from the Walter Reed National Military Medical Center for coronavirus antibodies before and after obtaining the anti-Pfizer vaccine. Participants were all healthy, non-immunocompared and are not positive for COVID-19 at the time of their registrants. Researchers also had participants complete a questionnaire on theirSide effects induced by the vaccine After each dose, measure the duration and severity of 12 symptoms on a scale of 0 (not at all) to 4 (many). They then performed antibody tests 37 days on average after their second dose.

When comparing the participants' antibodies, the authors wrote: "We did not find any correlation between the severity scores of the symptoms associated with the vaccine and the antibody titles induced by the vaccine one month after vaccination." They added that the duration of the side effects after the first and second doses of Pfizer also "revealed no association" with an antibody response. "[A] The absence of correlation has been observed even when adjusting age, weight and sex," the authors explain.

In the end, the researchers concluded that a "lack of post-vaccination symptoms after receipt of the BNT162B2 [Pfizer] vaccine does not correspond to the lack of antibody induced by the vaccine after vaccination". And that led them to two important conclusions. "First, individuals who have few symptoms after vaccination can be reassured that this does not mean that the vaccine" did not work ". Indeed, in this cohort, people with little symptoms to any symptoms N ' Although likely to have developed strong antibody responses as individuals who have presented substantial symptoms. Secondly, the immunological routes responsible for [side effects] induced by the mRNA may not be necessary for the development of Responses of robust antibodies. "

This is also worthless only in the real world, a vast majority of people who have been vaccinated against COVID have not had side effects. In JuneEconomistYugov's Survey, 75% of people in the United States reported having no side effects after receiving COVID vaccine andPfizer recipients In particular, were less likely to have adverse effects: only 19% of the people who have obtained the vaccine against Pfizer saidhad a reaction.

So, if you were among the many who got your pfizer shots and you felt a little else, but a bit in the arm and some pain, or maybe even emerging completely without Scot, rest assured that 'There is no reason to believe the vaccine and your immune system did not work.

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