If you have Johnson & Johnson, this is when you need a booster spectacles, study
The company said a second shot of their dose vaccine generated a strong immune response from.
The health authorities answered months of questions when they recently announcedCOVID-19 boosters of vaccines would be made available to the general public. But the decision to recommend a third dose of mRNA vaccines such as Pfizer or moderna to eight months also those who have left a single-dose vaccine with questions about when they might need to get an extra. Now a new study by Johnson & Johnson found that obtaining aReminder at least six months After the initial dose can help strengthen the immune system.
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The data comes from phase 2 studies conducted by the pharmaceutical company that tested the antibodies of about 2000 people whogot a reminder of the vaccine Six months after their first shot. The additional dose generated a powerful immune response among participants in the study between the ages of 18 and 55, as well as in patients aged 65 and when they received a lower dose as a recall injection.
"New provisional data of these studies show that Johnson & Johnson Covid-19 recall dose generated a rapid and robust increase in peak-binding antibodies, nine times more than 28 days after the primo-vaccination. Single dose The company said in his statement.
The company now plans to submit data from the study to Food & Drug Administration (FDA) for permission to beadministered as a recall injection. If it is approved, the extra gunshots could start deploying with Pfizer and Moderna in September for all who received their initial doses eight months earlier.
"We have established that a single shot of our CVIV-19 vaccine generates strong and robust immune responses that are durable and persistent in eight months. With this new data, we also see that a booster of Johnson & Johnson Covid-19 vaccine other antibody responses increase among participants who have already received our vaccine, "Mathai Mammen, MD, Janssen's World Research and Development Manager, said in the statement published by the company. "We are looking forward to talking with public health a potential strategy for our Johnson & Johnson Covid-19 vaccine, increasing eight months or more after single-dose primo-vaccination. »
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After the recall or effectiveness against the new strains such as the Delta variant of the Company's declaration did not mention the levels of vaccine efficiency. But in a recent study by South Africa published on August 6 found, it was found that a single shot was95 percent effective to prevent death and 71 percent effective to prevent hospitalization of a Delta variant infection.
vaccine experts weighed on the initial declaration of society, with optimism expressing that the second shot would be aEffective Defense against Covid. "The six-month boost is very impressive and significantly greater than what has already been reported in terms of two months, and which is important because, in my opinion, the boost should not be two months old, but it should really be six months later, "Dan Barouch, MD, Vaccine Researcher in Beth Israel DeaConness Medical Center and Harvard Medical School, who did not participate in the J & J study, told CNN.
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Barouch too continued to dispel the initial doubts that a reminder J & J would be ineffective because of his design. "There was a theoretical concern that the generation of anti-vector antibodies by the first shot could prevent the use of new," he told CNN. "I think this data put that to rest. »
Asked about the approval process for the extra shot, Barouch remains confident that he would be seen through. "I am quite certain that the FDA, [Centers for Disease Control and Prevention] NIH, and the White House will use this data to probably justify or recommend a reminder for J-vaccinated people , probably with a second J & J coup, "he said.
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