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Vaccines against COVID-19are not mandated; They are a choice. Dr. Paul Offers, a member of the FDA vaccines and related organic product advisory committee and director of the Philadelphia Children's Hospital Immunicity Center, was a guest on"Radio radio" from Siriusxm radio with Dr. Marc SiegelAnd talked about the impact that the choice will have if not enough people are vaccinated. Read on what this will involve and to ensure your health and health and health of others, do not miss these Without signs that you have already had coronavirus.

"What worries me is that we do not now know the impact of those who choose not to have a vaccine because we do not have enough vaccine yet," said Offit. "In the summer, we will have enough vaccine. And you may see that we may get 60% of people who have vaccinated or 70% of people. And then you have a solid 30% of People who choose not to be vaccinated ... Surveys for people who identify up as Republicans have shown that 46% of Republican men stated that they would not receive vaccine. I mean, and then You? I mean then if it comes to, that we do not have a high vaccination rate in next winter, and it's up to his winter virus, then we will not have a bump winter Next, we will have an overvoltage next winter. And what? I mean, do we consider it good for people to say that I choose as a question of my own freedom to allow me to catch and transmit a potentially fatal infection, or enter and engage a certain level of mandate? We will see. "

"It's possible," he said. "We certainly know that courier RNA vaccines induce very good cellular immune responses. T Cytotoxic T cells, cytotoxic T cells that generally predicts quite sustainable immunity. I mean, the immunity that could well, well In recent years. It's not clear. For me exactly how long we know how long the long immunity is with human coronaviruses. There were studies carried out in the early nineties, suggesting that he Lure at least a year and that it probably lasts longer, but there are certainly examples of medicine where the vaccine induces a better immune response and a longer immune response than natural infection. It is true of the vaccine against The human papillomavirus, it is true of tetanus vaccines, it is true of the conjugate hemophilus influenza type B and pneumococcal vaccine. This can be examples of that. It can be that. E Show, when you see, for example, people get a vaccine and having a so-called Ipsilateral meaning meaning the same ease, an involvement of the lymph ganglion, it's pretty incredible. We give al ot of vaccines and do not generally see sort of lymph nodes enlarged under the arm at the same arm that was inoculated. You would see this with the smallpox vaccine, which was another powerful immunogen. And this maybe, I mean, we learn about mRNA vaccines. They certainly seem to be powerful immunizations. "

"The clinical trials of 12-year-olds have therefore been fully recruited," he said. "And I suspect that we will have information about it at the beginning of the summer. The type of testing that is done are not like the efficiency tests that were made for Pfizer, Moderna, J & J, which is to tell tens of thousands of people who get or do not receive vaccine. I think what it's going to be just so-called immunogenicity tests, where you make sure you have the right dose, that You have the right dosing interval, which you induce an immune response, likely to protect, then move forward from there. So, I think it is very possible that we can have vaccines in the older children aged 12 to 18 years. Now some of these companies fall to six months of age, and I think the next round will probably not be fully recruited and analyzed, at least I would imagine up to six years , not so much at six months, but up to six years old., Probably at the beginning of the next year born. So that we would have a vaccine for younger children early next year. I think children should be vaccinated. Last year, about 170 years old and children died of Covid-19. This is about the same number as influenza each year, for which we also have a vaccine, and chicken chickenness would kill 75 to 100 children a year. So it's not out of this kingdom. In addition, I'm on the service this week and I certainly see children in our hospital who have the so-called multi-system inflammatory disease, which can be difficult and for which once again, we could argue that children need 'a vaccine. "

AstraZeneca incorrectly reported its results in a press release. "It's a lot to whisper the line in any way," said Offit. "I mean, as a scientist, what you really want to see is published data. The data that has been examined in detail, then formulated published. So, you can watch all the details. I mean, as a that FDA vaccine advisory advice, we have this advantage, that when a product is subject to the license in this case of approval by the emergency authorization, we may consider all such data provided by The company and data provided by the FDA where they examine all the data of the company, just in case the company does not include. So we have all this information. Otherwise, we simply try to read the tea leaves in the Press releases, which I think is very frustrating for everyone. "

The Europeans paused the Astrazeneca vaccine for fear of a connection to blood clots. "If you look at the kind of blood clot history, blood clots are common," said Dr. Offit. "It is estimated that there is between 300,000 and 600,000 blood clots per year in the United States , Generally, deep vein thrombosis, there are even advertisements for products to treat or prevent deep vein thrombosis, which can then cause blood clots in the lungs, so-called embolism pulmonary. I think what was a little disturbing about this product, the vaccine against Oxford Astrazeneca was that there was a so-called central venous thrombosis, which means blood clots in the brain, which are not so common. And there was at least the group of AKA of 17 cases of these kinds of blood clots, all within two weeks of a dose of vaccine who is generally women and young women. And that was disturbing. So you would like to see all this data, see if there were other risk factors in these people, see if, it's really a substantive rate, which will depend on the number of people vaccinated. So, otherwise it's very frustrating, I think try to read the tea leaves. "

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"Then Pfizer and Moderna are two of the mRNA vaccine manufacturers," he said. "I mean that the dose of these vaccines is in the case of pfizer thirty micrograms, in the case of moderna, one hundred micrograms. A microgram is therefore a millionth of grant. You can make kilograms of that. I mean, It's nine newspapers, more what is to say, you can make billions of doses of this vaccine for a world that has more than 7 million people. There are therefore every reason to believe that mRNA vaccines can be the vaccines of the world. The problem, the difficult problem is lipid nanoparticle. I mean, it's not easy to produce mass. "As for yourself, get vaccinated when it becomes at your Disposition and protect your life and the lives of others, do not visit these elements. 35 places you are most likely to catch Covid .