Doctor says these existing medications can help Long Covid
Dr. Patterson of Édelldx aims for the vascular problem in the heart of PASC.
The race to find a healing or at least a little relief forCap is up to 30% of those who getCOVID will develop long Covid. The syndrome, formally called post-acute sequela of SARS-COV-2 infections (PASC), can result in fatigue, migraines, cerebral fog, post-existing discomfort and strange symptoms, many of which can ruin your life. As researchers around the world are trying to solve the problem, Dr. Bruce Patterson, ofInculdx, think his team has cracked him. Long Covid is a vascular problem, he says and treats it with a combination of existing drugs can lead to quick recovery. It has set up blood panels and infrastructure working with doctors in your state; Now it's just hanging, he says. Read it for its grip and how you could try it (keep in mind that it is still early stages) - and to ensure your health and health of others, do not miss theseSure sign that you have "Long" Covid and may even know.
Is there a kind of hope on the horizon, whether you or someone else, and how far is this horizon?
Dr. Patterson: Oh my God. Yes. I will give you a little narrative. Towards June of 2020, we completed a number of different clinical trials. And what we have noticed is that people were released from the hospital, they were alive, but without stretch of imagination, was their normal immune system. And then we started to hear about patients, some of whom were in some of these trials, who always have symptoms three and four months again, it was both at the beginning. So we started investigating what their immune profile looked like. And then we have developed an automatic learning computer program. And what we did is that we compared the immune profiles of acute Covid with, basically, long carriers. And it was completely different and abnormal.
The long American carriers knew that, but doctors did not know at first.
Dr. Patterson: As I am going to tell you, where are we, we have already treated more than 2,000 long lengths. And I would say 98% successfully, getting them better and recover them. The fact is that we noticed this immunological anomaly, we applied the learning of the machine and Ai, and it was actually a very distinct immunological entity. And so, the mark was this vascular inflammation. Now, why is it so important? Well, the blood vessels are omnipresent and this vascular inflammation occurs in the brain. This happens in your organs, it happens in the lungs, the chest, the heart. I mean, it is a unifying hypothesis that these blood vessels make, damage and causing inflammation in this generalized geography that we call the human body and that we can account for all the symptoms.
Why does this happen so?
Dr. Patterson: We have seen anomalies in some white blood cells called monocytes. We examined further and we found the monocyte protein, 15 months after infection, without viruses. There is no RNA, there is no replication skill. We proved that in the last article using the following generation sequencing, but we seques the entire genome of the virus and we found that there were just rrnum fragments and nothing to be able to create a new viral particle. However, the cells carried a covidation protein all over the body and caused inflammation. The most interesting thing number two is that the cells have a propensity to bind the blood vessels through a path called fractalcin. And number three, which is the kind of most directly applicable on a daily basis, the cells are mobilized by the exercise and a person the long carriers have intolerance to the exercise.
Yes, for me, the effort feels like a poison.
Dr. Patterson:And the good news is that we treat the two routes involved. Number one, the mobilization of these cells to treat with what is called CCR5 antagonists, which prevent cells from moving in areas of inflammation and number two, using statins to block this fractal channel that allows To these cells to find the blood vessels and cause vascular inflammation. It's like we're there there. And the answer has been remarkable. And we are even starting to treat post-lyme, fibromyalgia and chronic fatigue. Post-Lyme patients reported on this drug regime, they never felt better. So we really think it could have very very serious implications for many of this unexplained post-infective syndrome.
So how long does it take this treatment? And will I ever be able to get me exercising again?
Dr. Patterson:As we deal with, you know, four to six weeks, what we do when we restore the immune system and the immune profile to normal, is that we begin while they are in medicine, increasing their exercise and their activity. We therefore disturred their system, knowing that we reduce a number of these cells containing covidation and that we keep them binding to blood vessels, which causes the symptoms. We therefore increase their activity, while in drugs while we follow them. They will go better, you will get better. You will come back to what you are used to doing, and it's not something you're going to have to treat long.
Are there any disadvantages to this treatment? Side effects?
Dr. Patterson:To tell you the truth, they are relatively benign. I mean, one of the drugs we use there has been this long and long discussion about the potential toxicity of the liver of one of the original tests 12 years ago. And then, there were subsequent papers, the NIH and the five-year security profile of this medicine, if you take it every day. But we are talking about four to six weeks, you know? The other thing is that this drug with supposed hepatic toxicity has been demonstrated to be safe in children. So, you know, what nothing says safety better than safety in children. We are watching so that it does not deceive me, where we are very conservative, but we have had more hepatic toxicity of people who take too much Tylenol than anyone of this medicine.
So, six weeks ago, then the person does not have Covid cells that follow them?
Dr. Patterson: He drops, the patients we followed. And again, it's still in the field of research. We have not launched clinically, as we have launched our immune profile and that the learning of the machine and the AI algorithm contribute to calculating how they do - it's all in key licensed laboratories and function officially with approved reports. We set up laboratories right now in the EU, the United Kingdom, Latin America, Mexico. We will globalize with this program.
So, how can a long carrier get the treatment you are talking about?
Dr. Patterson: We have therefore designed our panels specifically for Covid and Long Covid. So our panel will generate a gravity score, if you have acute coovidants, to see who will become severe. It will then generate what is called what is called a "long-term index" for those who are, uh, long carriers. Thus, this special and patented group that we have developed is offered through two reference laboratories in the United States. So what you would do is right, we have a websitewww.covidlonghaulars.comAnd it is very friendly: you sign up for your blood to be tested. Your doctor next can send blood to one of these two laboratories. The results come back, you organize telemedicine with one of our telemedicine doctors and you can make these appointments on this site. Then, the telemedicine group makes recommendations on the therapy, which we then send to primary care physicians to prescribe and follow patients in therapy. And we have more hundreds of doctors in our national network, representing all 50 states, who bought in the program, bought in the therapy, saw success in their patients and were really linchpin in the manufacture of this work Where we suffice to act as a test laboratory in the interpretation of test results, with regard to the therapies would be the best. And then they are the real leaders on the front line implementing the therapies.
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You mentioned post-exertion symptoms. Let's go through some more symptoms. How about brain fog?
Dr. Patterson: It's a really important issue. The bottom line is these cells that contain covidation proteins, go through the blood-cerebral barrier and cause vascular inflammation in the brain. OK? And when they, when these cells bind to the blood vessels, they release a compound called VEGF. The VEGF we found is strongly correlated with peripheral neuropathy, numbness and weakness of tingling, neuropathic symptoms. The other thing happens when you get this inflammation of the blood vessel, there is a vasodilatation. What does vasodilatation cause? Headache, migraines? Yes. And vascular information of course come from brain fog and what we call tinnitus or ringtone into the ears. The drug agonist we use has been incredible to reduce brain fog and 10 of that within three to five days. We therefore call our brain fog killer. And then, it also reduces the VEGF - the vascular endothelial growth factor - which causes peripheral neuropathic symptoms.
And some patients mentioned a "cytokine storm" - as their immune system is buzzing?
Dr. Patterson: We determined which symptoms are caused by which elevations of cytokine. All we do is a precision medicine using diagnostics to determine therapy. And what we can do is say, okay, here is your immune profile while here are your abnormal laboratory results. This is what we need to use to target these abnormal laboratory results. And yes, it usually ends up with a combination of the two drug classes that I mentioned that address vascular inflammation, but we use other drug-fluvoxamine is a good drug to reduce cytokine levels, such as ivermectin to a certain extent.
And fatigue?
Dr. Patterson: Usually, when your inflammation decreases, fatigue leaves, you start having more energy.
And shortness of breath?
Dr. Patterson: Some people have this very interesting thoracic pain where there is a breathlessness perception, but they are not really breathless. You do oxygen and you are normal. And what I think it's caused by the lungs of the lungs, called the pleura, is inflamed. The diaphragm is inflamed, the thoracic wall is inflamed because there is a membranous lining on the big bone and the sternum or the bone of the chest, all the membranes are inflamed. And it is the mechanical movement to take a breath that makes you feel as if you are out of breath when your oxygen exchange is perfectly normal. Vascular inflammation is something that is so universal that it really helps to explain all these symptoms that seem unusual. For us, having studied it for the moment 14 months, it is no longer this unusual.
As for yourself, to cross this pandemic with your healthiest, do not miss these35 places you are most likely to catch Covid.